HitPredict

Interactor 1: ROA3 (P51991)
Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
Gene: HNRNPA3

Interactor 2: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26777405
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 378 Hs			1 466
+	Hs
		1100952 MSI2H_HUMAN (18-364): 7.33e-58: 193: 29.97		G3BP1_HUMAN (1-466): 3.24e-102: 315: 100.00
+	Hs
		1100765 HNRPD_HUMAN (8-250): 1.57e-56: 190: 34.98		G3BP1_HUMAN (1-466): 3.24e-102: 315: 100.00
+	Hs
		1100981 ROAA_HUMAN (12-208): 7.26e-36: 135: 38.38		G3BP1_HUMAN (1-466): 3.24e-102: 315: 100.00
+	Hs
		1120393 HNRPD_HUMAN (8-250): 1.57e-56: 190: 34.98		G3BP2_HUMAN (1-463): 6.64e-76: 247: 58.68
+	Hs
		485112 ROA1_HUMAN (8-116): 3.12e-19: 89.8: 29.20		G3BP1_HUMAN (1-466): 3.24e-102: 315: 100.00
+	Hs
		1120163 HNRPD_HUMAN (8-250): 1.57e-56: 190: 34.98		SAFB1_HUMAN (93-439): 1.21e-34: 139: 12.39
+	Hs
		65293 MSI1H_HUMAN (19-364): 5.59e-59: 196: 27.78		RFOX3_HUMAN (258-465): 5e-34: 131: 15.71
+	Hs
		172159 HNRDL_HUMAN (20-303): 9.66e-70: 226: 32.30		CELF1_HUMAN (330-419): 4.38e-12: 70: 14.29
+	Dm
		1344374 Q9VBQ1_DROME (119-239): 7.18e-25: 108: 26.45		Q8SYC0_DROME (23-421): 1.35e-51: 180: 12.69
+	Hs
		909641 ROA3_HUMAN (1-224): 5.11e-61: 202: 100.00		CELF1_HUMAN (330-419): 4.38e-12: 70: 14.29
+	Hs
		214315 MSI1H_HUMAN (19-364): 5.59e-59: 196: 27.78		CELF5_HUMAN (301-424): 8.94e-14: 75: 16.92
+	Hs
		214324 MSI1H_HUMAN (19-364): 5.59e-59: 196: 27.78		CELF1_HUMAN (330-419): 4.38e-12: 70: 14.29
+	Hs
		1120264 HNRPD_HUMAN (8-250): 1.57e-56: 190: 34.98		CELF1_HUMAN (330-419): 4.38e-12: 70: 14.29
+	Dm
		877797 RB97D_DROME (24-211): 1.69e-44: 161: 47.12		RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15
+	Hs
		1369827 ROAA_HUMAN (12-208): 7.26e-36: 135: 38.38		CELF1_HUMAN (330-419): 4.38e-12: 70: 14.29
+	Dm
		1303362 Q8IMS8_DROME (119-239): 2.91e-25: 109: 26.45		Q8IP90_DROME (331-421): 1.13e-14: 78.5: 19.59
+	Hs
		650883 ROA2_HUMAN (8-126): 3.56e-26: 109: 29.27		CELF1_HUMAN (330-419): 4.38e-12: 70: 14.29
+	Dm
		877795 RB87F_DROME (1-117): 3.63e-24: 104: 25.62		RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15
+	Dm
		462179 ROA1_DROME (114-211): 4.8e-21: 95.2: 29.59		RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15
+	Hs
		333772 ROA1_HUMAN (8-116): 3.12e-19: 89.8: 29.20		CELF2_HUMAN (318-402): 5.34e-12: 69.7: 17.78