HitPredict

Interactor 1: COBL1 (Q53SF7)
Cordon-bleu protein-like 1
Gene: COBLL1

Interactor 2: PACN3 (Q9UKS6)
Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511)
Gene: PACSIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1128 Hs			1 424
+	Hs
		1121928 COBL1_HUMAN (1-1128): 3.38e-154: 491: 100.00		PACN1_HUMAN (4-422): 1.04e-84: 267: 48.86
+	Hs
		1121933 COBL1_HUMAN (1-1128): 3.38e-154: 491: 100.00		PACN2_HUMAN (4-422): 2.86e-77: 249: 48.96
+	Hs
		254836 COBL_HUMAN (1-1114): 5.17e-61: 230: 19.41		PACN3_HUMAN (1-424): 1.71e-91: 284: 100.00
+	Hs
		254822 COBL_HUMAN (1-1114): 5.17e-61: 230: 19.41		PACN1_HUMAN (4-422): 1.04e-84: 267: 48.86
+	Rn
		88744 COBL_RAT (17-1112): 2.45e-58: 221: 18.21		PACN1_RAT (1-422): 6.1e-86: 270: 48.53
+	Hs
		254837 COBL_HUMAN (1-1114): 5.17e-61: 230: 19.41		PACN2_HUMAN (4-422): 2.86e-77: 249: 48.96
+	Hs
		1329254 TARA_HUMAN (116-1127): 1.25e-16: 87.8: 9.49		PACN3_HUMAN (1-424): 1.71e-91: 284: 100.00
+	Hs
		1315994 TARA_HUMAN (116-1127): 1.25e-16: 87.8: 9.49		PACN1_HUMAN (4-422): 1.04e-84: 267: 48.86
+	Hs
		203260 SYNJ1_HUMAN (275-745): 8.6e-10: 65.3: 11.45		PACN3_HUMAN (1-424): 1.71e-91: 284: 100.00
+	Hs
		1329256 TARA_HUMAN (116-1127): 1.25e-16: 87.8: 9.49		PACN2_HUMAN (4-422): 2.86e-77: 249: 48.96
+	Hs
		203251 SYNJ1_HUMAN (275-745): 8.6e-10: 65.3: 11.45		PACN1_HUMAN (4-422): 1.04e-84: 267: 48.86
+	Hs
		203262 SYNJ1_HUMAN (275-745): 8.6e-10: 65.3: 11.45		PACN2_HUMAN (4-422): 2.86e-77: 249: 48.96
+	Hs
		203224 SYNJ1_HUMAN (275-745): 8.6e-10: 65.3: 11.45		MYO1E_HUMAN (2-422): 5.28e-39: 151: 14.03
+	Hs
		203228 SYNJ1_HUMAN (275-745): 8.6e-10: 65.3: 11.45		ITSN1_HUMAN (30-424): 3.23e-15: 80.2: 10.78
+	Hs
		203246 SYNJ1_HUMAN (275-745): 8.6e-10: 65.3: 11.45		SH3Y1_HUMAN (308-419): 5.4e-12: 68.7: 24.78