HitPredict

Interactor 1: ARHG7 (Q14155)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)
Gene: ARHGEF7

Interactor 2: ZYX (Q15942)
Zyxin (Zyxin-2)
Gene: ZYX

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32203420
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CH~LIM
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 803 Hs			1 572
+	Hs
		253950 ARHG7_HUMAN (1-803): 0: 672: 100.00		LPXN_HUMAN (221-570): 4.44e-48: 174: 18.18
+	Hs
		878455 ARHG7_HUMAN (1-803): 0: 672: 100.00		PAXI_HUMAN (5-500): 2.09e-31: 130: 13.85
+	Mm
		1354128 ARHG7_MOUSE (1-792): 0: 587: 91.79		PAXI_MOUSE (5-500): 6.87e-29: 123: 14.61
+	Hs
		253953 ARHG6_HUMAN (1-762): 1.38e-166: 503: 53.32		LPXN_HUMAN (221-570): 4.44e-48: 174: 18.18
+	Hs
		878462 ARHG6_HUMAN (1-762): 1.38e-166: 503: 53.32		PAXI_HUMAN (5-500): 2.09e-31: 130: 13.85
+	Hs
		878582 PKHG1_HUMAN (236-776): 1.78e-79: 281: 19.65		PAXI_HUMAN (5-500): 2.09e-31: 130: 13.85
+	Hs
		1123119 PKHG2_HUMAN (243-649): 4.14e-79: 280: 21.96		FHL2_HUMAN (468-572): 2.69e-19: 90.1: 21.91
+	Hs
		1372011 PKHG2_HUMAN (243-649): 4.14e-79: 280: 21.96		LPP_HUMAN (4-495): 2.71e-13: 74.7: 13.92
+	Hs
		1154088 ITSN1_HUMAN (26-244): 4.97e-10: 65.5: 14.63		ZYX_HUMAN (1-572): 1.57e-71: 241: 100.00
+	Hs
		1154154 ITSN1_HUMAN (26-244): 4.97e-10: 65.5: 14.63		AJUBA_HUMAN (96-572): 1.55e-57: 203: 22.35