Protein: PKHG1
Pleckstrin homology domain-containing family G member 1

Gene: PKHG1, PLEKHG1
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q9ULL1

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0031267 - small GTPase binding
GO:0051056 - regulation of small GTPase mediated signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

955749

CDC42
Cell division control protein 42 homolog

2

20

High-throughput

0.768

High

988820

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.647

High

1447425

ANLN
Anillin

1

3

High-throughput

0.618

High

1226319

CP135
Centrosomal protein of 135 kDa

2

6

High-throughput

0.584

High

1461636

NINL
Ninein-like protein

2

17

High-throughput

0.584

High

601497

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.553

High

1241059

L2GL2
LLGL scribble cell polarity complex component 2

1

1

High-throughput

0.536

High

1402001

GCP5
Gamma-tubulin complex component 5

1

0

High-throughput

0.513

High

706349

S10A2
Protein S100-A2

1

6

High-throughput

0.489

High

1461302

MYH13
Myosin-13

1

6

High-throughput

0.489

High

164129

NDC80
Kinetochore protein NDC80 homolog

1

13

High-throughput

0.479

High

173544

XPO1
Exportin-1

1

7

High-throughput

0.479

High

177332

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

8

High-throughput

0.479

High

179265

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

4

High-throughput

0.479

High

278993

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.479

High

317034

MTA2
Metastasis-associated protein MTA2

1

1

High-throughput

0.479

High

349290

LATS1
Serine/threonine-protein kinase LATS1

1

10

High-throughput

0.479

High

354423

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

4

High-throughput

0.479

High

437384

K2C8
Keratin, type II cytoskeletal 8

1

7

High-throughput

0.479

High

442523

GELS
Gelsolin

1

5

High-throughput

0.479

High

475058

VIME
Vimentin

1

13

High-throughput

0.479

High

475720

K1C19
Keratin, type I cytoskeletal 19

1

10

High-throughput

0.479

High

756084

MCM5
DNA replication licensing factor MCM5

1

5

High-throughput

0.479

High

878582

PAXI
Paxillin

1

17

High-throughput

0.479

High

958219

ARP3
Actin-related protein 3

1

6

High-throughput

0.479

High

967010

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

1049899

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1066545

RBBP4
Histone-binding protein RBBP4

1

4

High-throughput

0.479

High

1159048

RBBP7
Histone-binding protein RBBP7

1

5

High-throughput

0.479

High

1197124

AMOT
Angiomotin

1

14

High-throughput

0.479

High

1203289

ODFP2
Outer dense fiber protein 2

1

9

High-throughput

0.479

High

1215528

CE162
Centrosomal protein of 162 kDa

1

20

High-throughput

0.479

High

1227695

A16L1
Autophagy-related protein 16-1

1

15

High-throughput

0.479

High

1228493

FTM
Protein fantom

1

16

High-throughput

0.479

High

1323483

NUP93
Nuclear pore complex protein Nup93

1

1

High-throughput

0.479

High

1326377

NIN
Ninein

1

20

High-throughput

0.479

High

1333024

F184A
Protein FAM184A

1

7

High-throughput

0.479

High

1368971

GOGA1
Golgin subfamily A member 1

1

7

High-throughput

0.479

High

1391212

BICD1
Protein bicaudal D homolog 1

1

13

High-throughput

0.479

High

1403089

CEP89
Centrosomal protein of 89 kDa

1

15

High-throughput

0.479

High

1411369

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.479

High

1417208

SRRT
Serrate RNA effector molecule homolog

1

2

High-throughput

0.479

High

1431563

VP33B
Vacuolar protein sorting-associated protein 33B

1

3

High-throughput

0.479

High

1447527

XPP1
Xaa-Pro aminopeptidase 1

1

1

High-throughput

0.479

High

1448712

LATS2
Serine/threonine-protein kinase LATS2

1

12

High-throughput

0.479

High

1461633

RUVB1
RuvB-like 1

1

2

High-throughput

0.479

High

1461634

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

2

High-throughput

0.479

High

176573

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.458

High

290200

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

1143587

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.458

High

1149393

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1208601

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.458

High

1218078

CBPC6
Cytosolic carboxypeptidase 6

1

0

Small-scale

0.458

High

1365389

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

366382

PLMN
Plasminogen

1

2

High-throughput

0.437

High

833385

PERI
Peripherin

1

13

High-throughput

0.437

High

1117164

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.437

High

1208217

SPXN5
Sperm protein associated with the nucleus on the X chromosome N5

1

2

High-throughput

0.437

High

1242790

RL22L
Ribosomal protein eL22-like

1

3

High-throughput

0.437

High

1247538

POTEE
POTE ankyrin domain family member E

1

14

High-throughput

0.437

High

1252288

SYNE3
Nesprin-3

1

16

High-throughput

0.437

High

1256633

CE128
Centrosomal protein of 128 kDa

1

14

High-throughput

0.437

High

1288816

KTN1
Kinectin

1

11

High-throughput

0.437

High

1453573

TMOD2
Tropomodulin-2

1

11

High-throughput

0.437

High

1273211

CHSTF
Carbohydrate sulfotransferase 15

1

0

High-throughput

0.279

Low

1461635

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025