HitPredict

Interactor 1: TAB3 (Q571K4)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)
Gene: TAB3

Interactor 2: M3K7 (Q62073)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: Map3k7

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	36593296, 31127032, 19955178, 17384642
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 716 Mm			1 579
+	Hs
		201369 TAB3_HUMAN (1-716): 1.45e-113: 360: 94.83		M3K7_HUMAN (1-579): 0: 540: 94.88
+	Hs
		201449 TAB2_HUMAN (1-715): 1.97e-74: 256: 30.86		M3K7_HUMAN (1-579): 0: 540: 94.88
+	Mm
		1143268 TAB2_MOUSE (1-715): 3.29e-63: 225: 30.86		M3K7_MOUSE (1-579): 0: 556: 100.00
+	Rn
		473815 TAB2_RAT (1-715): 1.02e-62: 224: 30.99		M3K7_RAT (1-579): 0: 541: 95.05