HitPredict

Interactor 1: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Interactor 2: OTUB2 (Q96DC9)
Ubiquitin thioesterase OTUB2 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB2) (OTU domain-containing ubiquitin aldehyde-binding protein 2) (Otubain-2) (Ubiquitin-specific-processing protease OTUB2)
Gene: OTUB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	23105109
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 630 Hs			1 234
+	Hs
		186572 TRI18_HUMAN (4-629): 3.86e-113: 355: 22.47		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		1387347 TRIM1_HUMAN (3-629): 1.03e-105: 337: 20.44		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		1387333 TRIM8_HUMAN (7-365): 6.19e-76: 254: 23.98		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		623478 RO52_HUMAN (2-263): 6.24e-30: 125: 18.32		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		1387340 TRI39_HUMAN (4-490): 1.42e-29: 124: 15.23		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		1387334 TRIM5_HUMAN (2-246): 3.41e-29: 123: 17.74		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		572120 TRI27_HUMAN (7-471): 1.69e-28: 121: 13.46		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00