HitPredict

Interactor 1: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Interactor 2: Q6PK50 (Q6PK50)
HSP90AB1 protein
Gene: HSP90AB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FKBP_C~HSP90
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 351
+	Hs
		468370 FKBP8_HUMAN (1-412): 1.96e-100: 306: 100.00		HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00
+	Hs
		461475 FKBP8_HUMAN (1-412): 1.96e-100: 306: 100.00		HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92
+	Hs
		468302 PPID_HUMAN (5-369): 4.19e-65: 214: 18.33		HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00
+	Hs
		461404 PPID_HUMAN (5-369): 4.19e-65: 214: 18.33		HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92
+	Hs
		1125467 FKBP8_HUMAN (1-412): 1.96e-100: 306: 100.00		H90B4_HUMAN (25-328): 1.55e-133: 392: 83.22
+	Hs
		276662 FKBP6_HUMAN (81-380): 2.9e-56: 189: 23.73		HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00
+	Hs
		117613 FKBP6_HUMAN (81-380): 2.9e-56: 189: 23.73		K9JA46_HUMAN (1-350): 4.37e-172: 498: 84.92
+	Hs
		276661 FKBP6_HUMAN (81-380): 2.9e-56: 189: 23.73		HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92
+	Hs
		124722 AIP_HUMAN (97-369): 5.36e-53: 181: 18.94		HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00
+	Hs
		117612 AIP_HUMAN (97-369): 5.36e-53: 181: 18.94		K9JA46_HUMAN (1-350): 4.37e-172: 498: 84.92
+	Hs
		124718 AIP_HUMAN (97-369): 5.36e-53: 181: 18.94		HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92
+	Hs
		468890 FKBPL_HUMAN (8-369): 1.6e-49: 172: 22.34		HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00
+	Hs
		117626 FKBPL_HUMAN (8-369): 1.6e-49: 172: 22.34		K9JA46_HUMAN (1-350): 4.37e-172: 498: 84.92
+	Hs
		462017 FKBPL_HUMAN (8-369): 1.6e-49: 172: 22.34		HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92
+	Hs
		461989 AIPL1_HUMAN (91-374): 8.42e-48: 169: 17.12		HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92
+	At
		690690 FKB42_ARATH (53-391): 1.78e-57: 194: 23.43		HS901_ARATH (10-349): 1.46e-157: 459: 66.86
+	At
		690688 CYP40_ARATH (13-368): 7.48e-48: 168: 15.53		HS901_ARATH (10-349): 1.46e-157: 459: 66.86
+	Hs
		276703 FKBP6_HUMAN (81-380): 2.9e-56: 189: 23.73		Q86SX1_HUMAN (1-135): 3.67e-78: 242: 88.57
+	Hs
		124806 AIP_HUMAN (97-369): 5.36e-53: 181: 18.94		Q86SX1_HUMAN (1-135): 3.67e-78: 242: 88.57
+	Hs
		1286639 FKBPL_HUMAN (8-369): 1.6e-49: 172: 22.34		Q86SX1_HUMAN (1-135): 3.67e-78: 242: 88.57