HitPredict

Interactor 1: IQEC2 (Q5JU85)
IQ motif and SEC7 domain-containing protein 2
Gene: IQSEC2

Interactor 2: APBA2 (Q99767)
Amyloid-beta A4 precursor protein-binding family A member 2 (Adapter protein X11beta) (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2)
Gene: APBA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0098685 - Schaffer collateral - CA1 synapse
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1488 Hs			1 749
+	Hs
		1150553 IQEC1_HUMAN (234-1176): 0: 737: 58.25		APBA2_HUMAN (1-749): 0: 777: 100.00
+	Mm
		1125418 IQEC2_MOUSE (1-1488): 0: 1110: 98.25		DLG4_MOUSE (559-730): 2.81e-34: 142: 17.50
+	Hs
		1021511 IQEC2_HUMAN (1-1488): 0: 1123: 100.00		DLG1_HUMAN (442-730): 2.01e-28: 124: 16.24
+	Mm
		1143447 IQEC1_MOUSE (234-1165): 0: 736: 58.72		DLG4_MOUSE (559-730): 2.81e-34: 142: 17.50
+	Hs
		1021514 IQEC1_HUMAN (234-1176): 0: 737: 58.25		DLG1_HUMAN (442-730): 2.01e-28: 124: 16.24
+	Mm
		140105 CYH3_MOUSE (718-1084): 6.27e-111: 358: 24.94		DLG4_MOUSE (559-730): 2.81e-34: 142: 17.50
+	Mm
		926281 CYH2_MOUSE (696-1084): 5.46e-111: 358: 23.47		DLG4_MOUSE (559-730): 2.81e-34: 142: 17.50