Interactor 1: ITPR2 (Q14571)
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Inositol 1,4,5-trisphosphate receptor type 2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)
Gene: ITPR2
Interactor 2: TRPC4 (Q9UBN4)
Short transient receptor potential channel 4 (TrpC4) (Trp-related protein 4) (hTrp-4) (hTrp4)
Gene: TRPC4
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 1.00 | 0.713 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11163362 |
| Identification Methods | two hybrid, pull down |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ion_trans~Ion_trans |
| Common GO terms | GO:0005886 - plasma membrane GO:0070679 - inositol 1,4,5 trisphosphate binding |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025