HitPredict

Interactor 1: H2B2F (Q5QNW6)
Histone H2B type 2-F (H2B-clustered histone 18)
Gene: H2BC18

Interactor 2: SH24A (Q9H788)
SH2 domain-containing protein 4A (Protein SH(2)A) (Protein phosphatase 1 regulatory subunit 38)
Gene: SH2D4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 454
+	Hs
		561391 H2B2E_HUMAN (1-126): 3.79e-55: 169: 97.62		FER_HUMAN (147-445): 1.31e-41: 159: 16.99
+	Hs
		411752 H2B2F_HUMAN (1-126): 7.66e-56: 171: 100.00		LCK_HUMAN (220-446): 1.05e-41: 156: 17.01
+	Hs
		411835 H2B1M_HUMAN (1-126): 2.53e-55: 170: 95.24		LCK_HUMAN (220-446): 1.05e-41: 156: 17.01
+	Hs
		411664 H2B1C_HUMAN (1-126): 6.35e-55: 169: 98.41		LCK_HUMAN (220-446): 1.05e-41: 156: 17.01
+	Hs
		411813 H2B1H_HUMAN (1-126): 3.18e-55: 169: 99.21		LCK_HUMAN (220-446): 1.05e-41: 156: 17.01
+	Hs
		411656 H2B1D_HUMAN (1-126): 1.76e-54: 168: 97.62		LCK_HUMAN (220-446): 1.05e-41: 156: 17.01
+	Hs
		411834 H2B1N_HUMAN (1-126): 1.58e-54: 168: 97.62		LCK_HUMAN (220-446): 1.05e-41: 156: 17.01
+	Hs
		411836 H2B1L_HUMAN (1-126): 1.29e-53: 166: 96.83		LCK_HUMAN (220-446): 1.05e-41: 156: 17.01
+	Hs
		924623 H2B2F_HUMAN (1-126): 7.66e-56: 171: 100.00		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		924820 H2B1M_HUMAN (1-126): 2.53e-55: 170: 95.24		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		241496 H2B1K_HUMAN (1-126): 7.91e-55: 169: 97.62		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		883010 H2BFS_HUMAN (1-126): 7.4e-55: 169: 96.03		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		918279 H2B1C_HUMAN (1-126): 6.35e-55: 169: 98.41		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		924770 H2B1H_HUMAN (1-126): 3.18e-55: 169: 99.21		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		886077 H2B1D_HUMAN (1-126): 1.76e-54: 168: 97.62		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		924819 H2B1N_HUMAN (1-126): 1.58e-54: 168: 97.62		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		924821 H2B1L_HUMAN (1-126): 1.29e-53: 166: 96.83		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		557845 U3KQK0_HUMAN (1-126): 1.88e-56: 174: 97.62		NCK1_HUMAN (346-428): 3.27e-14: 75.7: 30.95
+	Hs
		557647 H2B1D_HUMAN (1-126): 1.76e-54: 168: 97.62		NCK1_HUMAN (346-428): 3.27e-14: 75.7: 30.95
+	Hs
		557738 H2B3B_HUMAN (1-126): 8.14e-53: 164: 95.24		NCK1_HUMAN (346-428): 3.27e-14: 75.7: 30.95