Interactor 1: LRRK2 (Q5S006)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-)
Gene: LRRK2
Interactor 2: LRRK2 (Q5S006)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-)
Gene: LRRK2
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.85 | 1.00 | 0.927 |
The method score is based on:
Property | Details |
---|---|
Experiments | 20659021, 17623048, 21390248, 27357661, 22952686 |
Identification Methods | enzymatic study, affinity chromatography technology, blue native page, electron microscopy, protein kinase assay, anti tag coimmunoprecipitation |
Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | COR~COR, COR~Roc, LRR_1~LRR_1, LRR_1~LRR_8, LRR_8~LRR_8, Pkinase~Pkinase, Roc~Roc |
Common GO terms | GO:0000139 - Golgi membrane GO:0000287 - magnesium ion binding GO:0001933 - negative regulation of protein phosphorylation GO:0001934 - positive regulation of protein phosphorylation GO:0003779 - actin binding and 126 others more... |
Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024