HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: FUBP2 (Q92945)
Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75)
Gene: KHSRP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	unassigned1853, 24725412
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2527 Hs			1 711
+	Hs
		1130419 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		FUBP1_HUMAN (70-707): 2.96e-89: 294: 58.65
+	Hs
		72991 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		B4DT31_HUMAN (51-707): 3.1e-84: 281: 56.28
+	Hs
		1130448 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		FUBP3_HUMAN (211-701): 4.22e-25: 112: 20.63
+	Hs
		1121934 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		Q53SS8_HUMAN (52-397): 2.33e-25: 110: 14.25
+	Hs
		128198 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		IF2B3_HUMAN (325-647): 8.75e-23: 105: 15.34
+	Hs
		1072105 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		PCBP2_HUMAN (52-400): 2.58e-22: 101: 15.28
+	Hs
		101720 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		F8VZX2_HUMAN (51-222): 5.45e-20: 93.6: 18.02
+	Hs
		101785 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		F8W930_HUMAN (61-211): 2.65e-10: 65.5: 20.26
+	Hs
		1130670 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		IF2B1_HUMAN (61-231): 3.23e-10: 65.5: 16.76
+	Hs
		73054 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		B4DUQ1_HUMAN (301-588): 1.1e-09: 63.2: 15.28
+	Hs
		782763 CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74		HNRPK_HUMAN (8-210): 5.64e-11: 67.3: 20.20
+	Hs
		903966 LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38		HNRPK_HUMAN (8-210): 5.64e-11: 67.3: 20.20