Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2
Interactor 2: DVL3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 0.60 | 0.573 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19625296 |
| Identification Methods | two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001934 - positive regulation of protein phosphorylation GO:0005829 - cytosol GO:0031267 - small GTPase binding GO:0035556 - intracellular signal transduction GO:0060070 - canonical Wnt signaling pathway |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
