HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: FUBP3 (Q96I24)
Far upstream element-binding protein 3 (FUSE-binding protein 3)
Gene: FUBP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0043025 - neuronal cell body
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2527 Hs			1 572
+	Hs
		1130419 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		FUBP1_HUMAN (16-565): 1.97e-104: 329: 52.53
+	Hs
		1130402 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		FUBP2_HUMAN (14-558): 1.18e-101: 324: 41.53
+	Hs
		72991 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		B4DT31_HUMAN (16-565): 4.56e-101: 321: 51.10
+	Hs
		128198 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		IF2B3_HUMAN (237-560): 9.9e-32: 131: 14.15
+	Hs
		1130670 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		IF2B1_HUMAN (237-560): 7.9e-26: 113: 15.69
+	Hs
		1072105 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		PCBP2_HUMAN (6-331): 5.08e-23: 102: 16.24
+	Hs
		101720 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		F8VZX2_HUMAN (6-331): 8.03e-22: 98.5: 16.72
+	Hs
		73054 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		B4DUQ1_HUMAN (254-507): 2.61e-16: 83.4: 14.12
+	Hs
		101785 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		F8W930_HUMAN (233-445): 6.62e-13: 73.4: 18.14
+	Hs
		1121934 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		Q53SS8_HUMAN (21-151): 5.83e-13: 72.3: 23.88
+	Hs
		782763 CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74		HNRPK_HUMAN (242-475): 5.55e-18: 88.8: 15.26
+	Hs
		903966 LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38		HNRPK_HUMAN (242-475): 5.55e-18: 88.8: 15.26