HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: DIDO1 (Q9BTC0)
Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)
Gene: DIDO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	29513927
Identification Methods	pull down, protein array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2527 Hs			1 2240
+	Hs
		1130774 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		PRC2C_HUMAN (27-1904): 3.9e-50: 199: 9.83
+	Hs
		257621 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		ANR17_HUMAN (1108-2079): 3.68e-42: 173: 12.34
+	Hs
		1075109 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		TCEA2_HUMAN (577-816): 6.11e-40: 153: 19.20
+	Hs
		92119 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		NACAM_HUMAN (6-1024): 1.9e-22: 108: 10.86
+	Hs
		867104 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		SC24C_HUMAN (1537-1898): 1.52e-16: 88.6: 19.74
+	Hs
		3594 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		A0A140VK53_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		782820 CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Dm
		1363782 Q9VDJ9_DROME (1810-2154): 3.35e-55: 216: 26.46		FUTSC_DROME (2-1740): 1.48e-32: 141: 10.60