HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: K1C23 (Q9C075)
Keratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23)
Gene: KRT23

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31046837
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2527 Hs			1 422
+	Hs
		359367 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		K1C14_HUMAN (70-416): 3.2e-146: 425: 43.79
+	Hs
		980269 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		K1C17_HUMAN (65-416): 3.98e-145: 421: 44.48
+	Hs
		72923 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		B4DN72_HUMAN (4-384): 2.56e-96: 298: 22.45
+	Hs
		1130283 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		K2C73_HUMAN (3-385): 1.66e-94: 295: 24.13
+	Hs
		445065 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		K1C16_HUMAN (68-394): 6.15e-88: 276: 47.87
+	Hs
		380486 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		K2C6B_HUMAN (36-401): 2.78e-80: 259: 20.60
+	Hs
		531584 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		K2C5_HUMAN (36-392): 8.92e-80: 258: 23.06
+	Hs
		3119 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		A0A0S2Z428_HUMAN (36-401): 8.06e-79: 255: 20.87
+	Hs
		1130353 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		Q8TC04_HUMAN (1-422): 5e-78: 249: 99.53