HitPredict

Interactor 1: ZBT14 (O43829)
Zinc finger and BTB domain-containing protein 14 (Zinc finger protein 161 homolog) (Zfp-161) (Zinc finger protein 478) (Zinc finger protein 5 homolog) (ZF5) (Zfp-5) (hZF5)
Gene: ZBTB14

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 449 Hs			1 768
+	Hs
		1042371 ZN184_HUMAN (103-448): 1.07e-134: 406: 20.33		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		73009 ZN879_HUMAN (151-448): 2.99e-126: 379: 20.87		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041826 Z585A_HUMAN (116-448): 1.01e-111: 347: 20.94		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042144 ZN480_HUMAN (166-448): 2.46e-114: 347: 22.11		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041813 ZN544_HUMAN (137-448): 2.62e-102: 322: 21.47		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042050 ZN565_HUMAN (99-448): 4.24e-104: 321: 22.47		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042314 ZN583_HUMAN (94-448): 1.56e-103: 321: 22.69		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042799 ZN229_HUMAN (123-448): 1.26e-93: 302: 22.26		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		988832 ZN33B_HUMAN (94-448): 4.7e-90: 291: 19.05		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		565092 ZNF7_HUMAN (187-449): 4.58e-90: 289: 24.31		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042755 ZN629_HUMAN (15-439): 2.1e-84: 278: 9.71		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041657 ZKSC8_HUMAN (137-415): 1.47e-83: 269: 25.09		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		196609 ZBT24_HUMAN (105-415): 1.82e-69: 235: 20.90		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042226 ZN566_HUMAN (211-409): 6.06e-71: 232: 29.15		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042316 ZN582_HUMAN (186-414): 3.24e-70: 232: 27.07		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1024288 ZBT17_HUMAN (212-415): 2.17e-62: 217: 29.90		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041738 ZN569_HUMAN (24-244): 4.96e-58: 204: 8.11		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042053 ZN527_HUMAN (98-449): 1.04e-55: 196: 17.51		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		563708 ZKSC1_HUMAN (311-448): 8.01e-54: 190: 30.00		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1043522 ZN582_HUMAN (186-414): 3.24e-70: 232: 27.07		CUL4B_HUMAN (5-768): 0: 779: 36.77