HitPredict

Interactor 1: STXB5 (Q5T5C0)
Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1)
Gene: STXBP5

Interactor 2: STX12 (Q86Y82)
Syntaxin-12
Gene: STX12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008021 - synaptic vesicle GO:0031201 - SNARE complex
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1151 Hs			1 276
+	Hs
		1083937 STXB5_HUMAN (1-1151): 0: 1143: 100.00		STX1A_HUMAN (17-273): 6.81e-67: 211: 23.19
+	Hs
		699268 STXB5_HUMAN (1-1151): 0: 1143: 100.00		STX2_HUMAN (16-272): 3.38e-66: 209: 26.62
+	Hs
		178582 STXB5_HUMAN (1-1151): 0: 1143: 100.00		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	Hs
		1017663 STXB5_HUMAN (1-1151): 0: 1143: 100.00		STX4_HUMAN (6-272): 1.25e-53: 177: 24.27
+	Hs
		1030154 STXB5_HUMAN (1-1151): 0: 1143: 100.00		STX3_HUMAN (5-250): 2.56e-53: 176: 25.20
+	Mm
		936826 STXB5_MOUSE (1-1151): 0: 1127: 96.88		STX4_MOUSE (6-273): 5.8e-54: 178: 25.28
+	Hs
		1205402 STB5L_HUMAN (1-1151): 0: 1051: 63.82		STX12_HUMAN (1-257): 2.32e-67: 212: 100.00
+	Hs
		699292 STB5L_HUMAN (1-1151): 0: 1051: 63.82		STX2_HUMAN (16-272): 3.38e-66: 209: 26.62
+	Ce
		183454 Q14DX2_CAEEL (14-1151): 0: 802: 34.99		STX1A_CAEEL (4-276): 2.41e-67: 212: 23.38
+	Hs
		178544 L2GL1_HUMAN (35-1142): 0: 697: 25.19		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	Hs
		1017639 L2GL1_HUMAN (35-1142): 0: 697: 25.19		STX4_HUMAN (6-272): 1.25e-53: 177: 24.27
+	Hs
		1030142 L2GL1_HUMAN (35-1142): 0: 697: 25.19		STX3_HUMAN (5-250): 2.56e-53: 176: 25.20