HitPredict

Interactor 1: NOLC1 (Q14978)
Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130)
Gene: NOLC1

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 699 Hs			1 726
+	Hs
		1039504 TOP2B_HUMAN (6-463): 6.99e-58: 215: 14.16		BRD3_HUMAN (1-702): 1.03e-155: 470: 100.00
+	Hs
		674165 NOLC1_HUMAN (1-699): 1.83e-63: 226: 100.00		BRD2_HUMAN (5-700): 8.79e-139: 429: 57.95
+	Hs
		674142 TOP2B_HUMAN (6-463): 6.99e-58: 215: 14.16		BRD2_HUMAN (5-700): 8.79e-139: 429: 57.95
+	Hs
		542523 TOP2A_HUMAN (6-372): 2.3e-38: 155: 14.44		BRD3_HUMAN (1-702): 1.03e-155: 470: 100.00
+	Hs
		542337 TOP2A_HUMAN (6-372): 2.3e-38: 155: 14.44		BRD2_HUMAN (5-700): 8.79e-139: 429: 57.95
+	Hs
		259963 NOLC1_HUMAN (1-699): 1.83e-63: 226: 100.00		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		259821 TOP2B_HUMAN (6-463): 6.99e-58: 215: 14.16		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		1141264 CHAP1_HUMAN (7-377): 7.52e-11: 67.8: 11.59		BRD3_HUMAN (1-702): 1.03e-155: 470: 100.00
+	Hs
		259357 TOP2A_HUMAN (6-372): 2.3e-38: 155: 14.44		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		674271 TITIN_HUMAN (19-560): 1.43e-11: 70.4: 12.03		BRD2_HUMAN (5-700): 8.79e-139: 429: 57.95
+	Hs
		260307 CHAP1_HUMAN (7-377): 7.52e-11: 67.8: 11.59		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		1039506 TOP2B_HUMAN (6-463): 6.99e-58: 215: 14.16		ZMY11_HUMAN (3-446): 3.19e-46: 176: 10.15
+	Hs
		1039486 TOP2B_HUMAN (6-463): 6.99e-58: 215: 14.16		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Hs
		542526 TOP2A_HUMAN (6-372): 2.3e-38: 155: 14.44		ZMY11_HUMAN (3-446): 3.19e-46: 176: 10.15
+	Hs
		1134496 NOLC1_HUMAN (1-699): 1.83e-63: 226: 100.00		PHIP_HUMAN (5-702): 1.66e-17: 89.5: 11.03
+	Mm
		1030125 TOP2A_MOUSE (6-368): 2.85e-44: 173: 16.17		PB1_MOUSE (4-415): 1.88e-30: 131: 12.11
+	Hs
		542483 TOP2A_HUMAN (6-372): 2.3e-38: 155: 14.44		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Hs
		542565 TOP2A_HUMAN (6-372): 2.3e-38: 155: 14.44		PB1_HUMAN (152-486): 2.23e-20: 99.1: 12.85
+	Hs
		1146251 TITIN_HUMAN (19-560): 1.43e-11: 70.4: 12.03		ZMY11_HUMAN (3-446): 3.19e-46: 176: 10.15
+	Dm
		1469891 ELYS_DROME (74-689): 5.29e-34: 142: 9.60		Q9VC36_DROME (52-201): 1.24e-17: 89.9: 21.33