HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 726
+	Hs
		674166 NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00		BRD2_HUMAN (5-700): 8.79e-139: 429: 57.95
+	Hs
		1134606 NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00		BRDT_HUMAN (18-694): 2.86e-116: 374: 49.78
+	Hs
		259964 NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		1067342 NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Hs
		936648 NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00		BRPF1_HUMAN (20-291): 2.19e-26: 117: 14.39
+	Hs
		1134630 NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00		PB1_HUMAN (152-486): 2.23e-20: 99.1: 12.85
+	Hs
		1134660 NUMA1_HUMAN (1-2115): 3.94e-159: 544: 100.00		PHIP_HUMAN (5-702): 1.66e-17: 89.5: 11.03
+	Hs
		1141129 EEA1_HUMAN (70-766): 2.58e-24: 114: 15.40		BRD3_HUMAN (1-702): 1.03e-155: 470: 100.00
+	Hs
		674197 CROCC_HUMAN (5-1053): 1.3e-28: 128: 11.58		BRD2_HUMAN (5-700): 8.79e-139: 429: 57.95
+	Hs
		1201938 CROCC_HUMAN (5-1053): 1.3e-28: 128: 11.58		BRDT_HUMAN (18-694): 2.86e-116: 374: 49.78
+	Hs
		259535 MYH9_HUMAN (1033-1891): 1.2e-33: 145: 10.62		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		259536 MYH10_HUMAN (1257-2089): 8.04e-33: 142: 11.87		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		260065 CROCC_HUMAN (5-1053): 1.3e-28: 128: 11.58		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		259978 PLEC_HUMAN (628-2114): 9.11e-27: 122: 10.00		BRD4_HUMAN (3-644): 3.51e-104: 349: 52.55
+	Hs
		772762 MYH9_HUMAN (1033-1891): 1.2e-33: 145: 10.62		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Hs
		773168 MYH10_HUMAN (1257-2089): 8.04e-33: 142: 11.87		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Hs
		1067348 EEA1_HUMAN (70-766): 2.58e-24: 114: 15.40		EP300_HUMAN (4-177): 1.06e-35: 148: 23.43
+	Hs
		1369203 CP250_HUMAN (1160-2114): 1.32e-28: 128: 11.27		KAT2B_HUMAN (267-414): 8.84e-32: 134: 25.50
+	Hs
		639735 EEA1_HUMAN (70-766): 2.58e-24: 114: 15.40		TAF1_HUMAN (20-303): 4.78e-19: 94.5: 13.73