HitPredict

Interactor 1: GRB2 (Q60631)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: VAV2 (Q60992)
Guanine nucleotide exchange factor VAV2 (VAV-2)
Gene: VAV2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 15102471
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~SH2, SH2~SH2, SH2~SH3_2, PH~SH3_1, RhoGEF~SH3_1, SH2~SH3_1, SH3_1~SH3_2
Common GO terms GO:0001784 - phosphotyrosine residue binding
GO:0005154 - epidermal growth factor receptor binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 217
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024