HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 10764587, 12893839
Identification Methods in-gel kinase assay, anti tag coimmunoprecipitation
Interaction Type phosphorylation reaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Pkinase, Ank_5~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 317
Hs

1 592
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024