HitPredict

Interactor 1: CCD18 (Q5T9S5)
Coiled-coil domain-containing protein 18 (Sarcoma antigen NY-SAR-24)
Gene: CCDC18

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1454 Hs			1 504
+	Hs
		1313550 CP250_HUMAN (190-1452): 3.17e-40: 166: 11.25		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		149418 CTRO_HUMAN (30-786): 2.21e-21: 103: 14.12		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		1067456 EEA1_HUMAN (584-1454): 2.14e-34: 146: 11.95		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		1061201 NUMA1_HUMAN (684-1451): 7.25e-32: 138: 13.30		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		724952 MYH9_HUMAN (811-1454): 5.19e-30: 132: 11.85		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		725215 MYH10_HUMAN (1-492): 3.94e-20: 99.9: 13.29		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		197084 CP250_HUMAN (190-1452): 3.17e-40: 166: 11.25		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84
+	Hs
		1061204 NUMA1_HUMAN (684-1451): 7.25e-32: 138: 13.30		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		1268063 MY18A_HUMAN (524-1183): 2.15e-13: 77.8: 20.43		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		728492 MYH11_HUMAN (2-540): 1.61e-20: 101: 11.21		POC1A_HUMAN (88-377): 5.18e-64: 215: 20.68
+	Hs
		149156 CTRO_HUMAN (30-786): 2.21e-21: 103: 14.12		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		903233 GOGB1_HUMAN (141-1453): 2.41e-34: 146: 10.97		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		148157 CTRO_HUMAN (30-786): 2.21e-21: 103: 14.12		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84
+	Hs
		792973 CENPE_HUMAN (96-868): 1.65e-11: 71.6: 13.45		LIS1_HUMAN (302-504): 3.93e-56: 194: 19.11
+	Hs
		551632 DESP_HUMAN (289-1164): 1.11e-10: 68.9: 19.50		LIS1_HUMAN (302-504): 3.93e-56: 194: 19.11
+	Hs
		148610 CTRO_HUMAN (30-786): 2.21e-21: 103: 14.12		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		903399 MY18A_HUMAN (524-1183): 2.15e-13: 77.8: 20.43		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		551655 DESP_HUMAN (289-1164): 1.11e-10: 68.9: 19.50		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		1061226 NUMA1_HUMAN (684-1451): 7.25e-32: 138: 13.30		KTNB1_HUMAN (282-504): 4.25e-12: 70.5: 27.07
+	Hs
		148858 CTRO_HUMAN (30-786): 2.21e-21: 103: 14.12		TAF5_HUMAN (233-434): 3.88e-16: 83.6: 26.60