HitPredict

Interactor 1: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Interactor 2: YTHD2 (Q9Y5A9)
YTH domain-containing family protein 2 (DF2) (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2)
Gene: YTHDF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30209976, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0010494 - cytoplasmic stress granule GO:0043488 - regulation of mRNA stability
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1133 Hs			1 579
+	Hs
		1136147 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTHD3_HUMAN (1-562): 2.13e-150: 446: 65.56
+	Hs
		1136271 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTHD1_HUMAN (1-579): 1.88e-139: 417: 62.20
+	Hs
		1136237 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTDC1_HUMAN (341-575): 6.57e-57: 205: 23.24
+	Hs
		1136291 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTDC2_HUMAN (285-556): 1.53e-54: 202: 20.50
+	Hs
		1335263 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD2_HUMAN (1-579): 1.24e-177: 516: 100.00
+	Hs
		1192380 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD3_HUMAN (1-562): 2.13e-150: 446: 65.56
+	Hs
		1317023 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD1_HUMAN (1-579): 1.88e-139: 417: 62.20
+	Hs
		1298137 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTDC1_HUMAN (341-575): 6.57e-57: 205: 23.24
+	Hs
		1332440 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTDC2_HUMAN (285-556): 1.53e-54: 202: 20.50