HitPredict

Interactor 1: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.753

Property	Details
Experiments	35271311, 26186194, 28514442, 33961781, 34761751, 19615732, 18922472, 19490896, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 389 Hs			1 329
+	Hs
		128093 PSD11_HUMAN (3-387): 8.58e-77: 245: 11.03		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Sp
		1082963 RPN7_SCHPO (9-387): 5e-95: 291: 42.78		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Sp
		1455129 RPN6_SCHPO (5-386): 3.55e-81: 256: 13.80		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Hs
		1136564 PSMD6_HUMAN (1-389): 5.6e-137: 397: 100.00		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		958685 CSN2_HUMAN (22-388): 5.39e-90: 280: 13.67		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		128031 PSD11_HUMAN (3-387): 8.58e-77: 245: 11.03		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		949408 EIF3E_HUMAN (26-387): 7.74e-74: 238: 14.04		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29