HitPredict

Interactor 1: PSD11 (O00231)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5)
Gene: PSMD11

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.753

Property	Details
Experiments	35271311, 26186194, 28514442, 33961781, 34761751, 19615732, 18922472, 19490896, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 422 Hs			1 329
+	Hs
		1136631 PSMD6_HUMAN (31-422): 1.03e-76: 245: 13.43		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		128348 PSD12_HUMAN (46-422): 3.5e-68: 225: 12.62		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Sp
		1455129 RPN6_SCHPO (13-419): 8.79e-92: 285: 54.90		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Sp
		1082963 RPN7_SCHPO (55-420): 3.49e-53: 184: 12.96		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Hs
		128031 PSD11_HUMAN (1-422): 1.14e-117: 351: 100.00		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		958685 CSN2_HUMAN (8-419): 1.12e-88: 277: 22.80		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		1136564 PSMD6_HUMAN (31-422): 1.03e-76: 245: 13.43		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		1364563 CSN4_HUMAN (4-422): 1.64e-71: 232: 14.62		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		128284 PSD12_HUMAN (46-422): 3.5e-68: 225: 12.62		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29