HitPredict

Interactor 1: SEPT2 (Q15019)
Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5)
Gene: SEPTIN2

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26496610, 31586073, 36526897
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0015629 - actin cytoskeleton GO:0030496 - midbody GO:0045296 - cadherin binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 361 Hs			1 1124
+	Hs
		1156423 SEPT7_HUMAN (11-357): 2.79e-171: 485: 53.61		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1365291 SEPT8_HUMAN (3-348): 2.75e-162: 464: 39.54		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1447400 SEPT9_HUMAN (2-320): 2.98e-159: 460: 45.68		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1447325 SEP11_HUMAN (8-348): 4.01e-161: 459: 39.83		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1121200 SEPT6_HUMAN (14-348): 5.21e-160: 457: 40.24		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1447375 SEP10_HUMAN (14-357): 7.52e-159: 454: 38.00		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		96007 E7EW69_HUMAN (14-357): 9.41e-159: 454: 38.00		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		828131 PNUT_DROME (6-347): 2.57e-175: 499: 51.60		ANLN_DROME (542-1112): 1.61e-160: 511: 29.84
+	Dm
		837970 SEPT1_DROME (9-336): 1.3e-175: 493: 72.97		ANLN_DROME (542-1112): 1.61e-160: 511: 29.84
+	Dm
		929191 SEPT2_DROME (2-357): 4.03e-156: 446: 40.06		ANLN_DROME (542-1112): 1.61e-160: 511: 29.84
+	Dm
		1267322 Q7KLG8_DROME (1-348): 1.07e-154: 443: 40.62		ANLN_DROME (542-1112): 1.61e-160: 511: 29.84