Protein: SEP10
Septin-10

Gene: SEP10, SEPTIN10
Organism: Homo sapiens
Interactions: 134
UniProt ID: Q9P0V9

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005940 - septin ring
GO:0008104 - intracellular protein localization
GO:0015630 - microtubule cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1156427

SEPT7
Septin-7

9

20

High-throughput

0.973

High

1365294

SEPT8
Septin-8

6

20

High-throughput

0.947

High

1137022

SEPT2
Septin-2

5

19

High-throughput

0.927

High

1121202

SEPT6
Septin-6

5

19

High-throughput

0.919

High

1406710

SEPT5
Septin-5

4

20

High-throughput

0.910

High

1450359

SEP11
Septin-11

4

19

High-throughput

0.903

High

1454083

SEPT3
Neuronal-specific septin-3

4

20

High-throughput

0.892

High

1315281

SEP12
Septin-12

3

20

High-throughput

0.861

High

1361615

SEPT1
Septin-1

3

19

High-throughput

0.861

High

1454084

SEPT9
Septin-9

3

20

High-throughput

0.861

High

210507

SEPT4
Septin-4

2

20

High-throughput

0.811

High

1256430

SEP14
Septin-14

2

20

High-throughput

0.811

High

1432839

BORG4
Cdc42 effector protein 4

5

14

High-throughput

0.712

High

890690

RGS3
Regulator of G-protein signaling 3

3

7

High-throughput

0.662

High

1145930

RBP1
RalA-binding protein 1

4

3

High-throughput

0.630

High

914783

RM12
Large ribosomal subunit protein bL12m

2

8

High-throughput

0.574

High

1390308

TRI11
E3 ubiquitin-protein ligase TRIM11

2

2

High-throughput

0.574

High

243168

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.533

High

1394200

LRCH3
DISP complex protein LRCH3

2

6

High-throughput

0.533

High

1447375

ANLN
Anillin

2

11

High-throughput

0.533

High

1399436

ACAP3
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

1

9

High-throughput

0.489

High

126847

RHOD
Rho-related GTP-binding protein RhoD

1

17

High-throughput

0.479

High

159894

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

5

High-throughput

0.479

High

340251

PCNT
Pericentrin

1

8

High-throughput

0.479

High

955697

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.479

High

988780

RAC1
Ras-related C3 botulinum toxin substrate 1

1

11

High-throughput

0.479

High

1038716

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

3

High-throughput

0.479

High

1143567

PCM1
Pericentriolar material 1 protein

1

1

High-throughput

0.479

High

1326367

NIN
Ninein

1

5

High-throughput

0.479

High

1387728

TBC31
TBC1 domain family member 31

1

3

High-throughput

0.479

High

1396649

RHOV
Rho-related GTP-binding protein RhoV

1

15

High-throughput

0.479

High

1396976

IFT74
Intraflagellar transport protein 74 homolog

1

4

High-throughput

0.479

High

1408550

AKAP9
A-kinase anchor protein 9

1

7

High-throughput

0.479

High

1433553

RHOJ
Rho-related GTP-binding protein RhoJ

1

14

High-throughput

0.479

High

1438210

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.479

High

290181

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

1350193

ALMS1
Centrosome-associated protein ALMS1

1

0

High-throughput

0.458

High

1359548

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.458

High

1454081

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.458

High

1454086

CP131
Centrosomal protein of 131 kDa

1

0

High-throughput

0.458

High

344573

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

1

High-throughput

0.439

High

67804

TBKB1
TANK-binding kinase 1-binding protein 1

1

7

High-throughput

0.437

High

159403

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

12

High-throughput

0.437

High

173482

XPO1
Exportin-1

1

10

High-throughput

0.437

High

177320

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

1

High-throughput

0.437

High

1217514

CE350
Centrosome-associated protein 350

1

6

High-throughput

0.437

High

208744

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

1

High-throughput

0.437

High

248120

NUPR1
Nuclear protein 1

1

2

High-throughput

0.437

High

257188

CCD22
Coiled-coil domain-containing protein 22

1

2

High-throughput

0.437

High

259150

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.437

High

331379

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.437

High

363951

EGFR
Epidermal growth factor receptor

1

15

High-throughput

0.437

High

465675

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.437

High

467635

4F2
Amino acid transporter heavy chain SLC3A2

1

3

High-throughput

0.437

High

535617

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.437

High

541728

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.437

High

610923

TCPA
T-complex protein 1 subunit alpha

1

6

High-throughput

0.437

High

634675

LMNB1
Lamin-B1

1

3

High-throughput

0.437

High

648705

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.437

High

668736

APC
Adenomatous polyposis coli protein

1

3

High-throughput

0.437

High

710908

EPHB2
Ephrin type-B receptor 2

1

13

High-throughput

0.437

High

799536

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.437

High

851433

PRS6B
26S proteasome regulatory subunit 6B

1

1

High-throughput

0.437

High

883955

CENPF
Centromere protein F

1

7

High-throughput

0.437

High

911886

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

3

High-throughput

0.437

High

931907

EPHA5
Ephrin type-A receptor 5

1

14

High-throughput

0.437

High

1008918

RED1
Double-stranded RNA-specific editase 1

1

4

High-throughput

0.437

High

1025857

BORG5
Cdc42 effector protein 1

1

14

High-throughput

0.437

High

1114503

CUL3
Cullin-3

1

2

High-throughput

0.437

High

1132350

GOGB1
Golgin subfamily B member 1

1

4

High-throughput

0.437

High

1150958

TRIPB
Thyroid receptor-interacting protein 11

1

5

High-throughput

0.437

High

1178644

KIF7
Kinesin-like protein KIF7

1

1

High-throughput

0.437

High

1191496

GRDN
Girdin

1

6

High-throughput

0.437

High

1251274

DNMBP
Dynamin-binding protein

1

8

High-throughput

0.437

High

1255884

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

1291596

HOOK3
Protein Hook homolog 3

1

4

High-throughput

0.437

High

1307210

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

4

High-throughput

0.437

High

1310176

GCC2
GRIP and coiled-coil domain-containing protein 2

1

4

High-throughput

0.437

High

1312385

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

1

High-throughput

0.437

High

1322804

CNTRB
Centrobin

1

3

High-throughput

0.437

High

1351397

DLG5
Disks large homolog 5

1

3

High-throughput

0.437

High

1371460

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

6

High-throughput

0.437

High

1384283

SH3K1
SH3 domain-containing kinase-binding protein 1

1

6

High-throughput

0.437

High

1388758

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

1

High-throughput

0.437

High

1396903

KI16B
Kinesin-like protein KIF16B

1

1

High-throughput

0.437

High

1400621

KI20B
Kinesin-like protein KIF20B

1

5

High-throughput

0.437

High

1401181

SPAG5
Sperm-associated antigen 5

1

3

High-throughput

0.437

High

1401844

TGS1
Trimethylguanosine synthase

1

3

High-throughput

0.437

High

1402916

CK5P2
CDK5 regulatory subunit-associated protein 2

1

6

High-throughput

0.437

High

1405812

TTC1
Tetratricopeptide repeat protein 1

1

2

High-throughput

0.437

High

1406297

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

1

High-throughput

0.437

High

1447272

KI13B
Kinesin-like protein KIF13B

1

2

High-throughput

0.437

High

1449213

KIF15
Kinesin-like protein KIF15

1

1

High-throughput

0.437

High

1454082

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.437

High

1454085

SNX6
Sorting nexin-6

1

1

High-throughput

0.437

High

1454087

ANR26
Ankyrin repeat domain-containing protein 26

1

1

High-throughput

0.437

High

1454089

SGT1
Protein SGT1 homolog

1

2

High-throughput

0.437

High

1167125

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

1

High-throughput

0.407

High

280964

HYPM
Huntingtin-interacting protein M

2

0

High-throughput

0.320

High

1404165

CD006
Uncharacterized protein encoded by LINC01587

2

0

High-throughput

0.318

High

300848

KRT38
Keratin, type I cuticular Ha8

1

0

High-throughput

0.279

Low

1178905

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1417891

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.279

Low

1398448

YTDC1
YTH domain-containing protein 1

1

0

High-throughput

0.251

Low

71773

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.249

Low

213263

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.249

Low

324225

CE152
Centrosomal protein of 152 kDa

1

0

High-throughput

0.249

Low

437371

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.249

Low

460649

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

High-throughput

0.249

Low

720809

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.249

Low

778797

PRS7
26S proteasome regulatory subunit 7

1

0

High-throughput

0.249

Low

943325

RBM11
Splicing regulator RBM11

1

0

High-throughput

0.249

Low

1031574

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.249

Low

1164607

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.249

Low

1178027

MOONR
Protein moonraker

1

0

High-throughput

0.249

Low

1198540

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.249

Low

1217572

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

0

High-throughput

0.249

Low

1233219

THOC7
THO complex subunit 7

1

0

High-throughput

0.249

Low

1289202

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.249

Low

1336223

RN214
RING finger protein 214

1

0

High-throughput

0.249

Low

1357435

DEP1B
DEP domain-containing protein 1B

1

0

High-throughput

0.249

Low

1383266

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

1385708

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

1389121

KBP
KIF-binding protein

1

0

High-throughput

0.249

Low

1390268

NRBF2
Nuclear receptor-binding factor 2

1

0

High-throughput

0.249

Low

1397843

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.249

Low

1405221

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.249

Low

1421219

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.249

Low

1433064

CA198
Uncharacterized protein C1orf198

1

0

High-throughput

0.249

Low

1436889

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.249

Low

1439175

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low

1447560

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.249

Low

1454088

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.249

Low

516882

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025