Interactor 1: OBSCN (Q5VST9)
Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)
Gene: OBSCN
Interactor 2: TITIN (Q8WZ42)
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene: TTN
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.944 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17716621, 23414517, 11448995, 20133654, 20489725 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, isothermal titration calorimetry, molecular sieving, two hybrid fragment pooling approach, fluorescent resonance energy transfer |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | fn3~fn3, I-set~fn3, Pkinase~fn3, I-set~I-set, I-set~Pkinase, PH~Pkinase, Pkinase~Pkinase, RhoGEF~fn3 |
| Common GO terms | GO:0004674 - protein serine/threonine kinase activity GO:0005516 - calmodulin binding GO:0005524 - ATP binding GO:0005829 - cytosol GO:0008307 - structural constituent of muscle and 5 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
