HitPredict

Interactor 1: ACAP2 (Q15057)
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)
Gene: ACAP2

Interactor 2: ACAP3 (Q96P50)
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (Centaurin-beta-5) (Cnt-b5)
Gene: ACAP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 33961781, 35271311, 31839598
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Ank_2, Ank_2~ArfGap, ArfGap~ArfGap, ArfGap~PH, BAR_3~BAR_3, BAR_3~PH, PH~PH
Common GO terms GO:0005096 - GTPase activator activity
GO:0008270 - zinc ion binding
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 778
Hs

1 834
+ Ce
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025