HitPredict

Interactor 1: MEF2A (Q60929)
Myocyte-specific enhancer factor 2A
Gene: MEF2A

Interactor 2: HDAC7 (Q8C2B3)
Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) (Protein deacetylase HDAC7) (EC 3.5.1.-)
Gene: HDAC7

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	16956611
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 498 Mm			1 938
+	Mm
		1207907 MEF2C_MOUSE (1-498): 5.43e-89: 282: 57.96		HDAC7_MOUSE (1-938): 0: 684: 100.00
+	Hs
		987223 MEF2C_HUMAN (1-498): 7.03e-88: 279: 58.15		HDAC7_HUMAN (23-938): 0: 638: 83.85
+	Hs
		968793 MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96		HDAC7_HUMAN (23-938): 0: 638: 83.85
+	Mm
		1157743 MEF2C_MOUSE (1-498): 5.43e-89: 282: 57.96		HDAC4_MOUSE (33-921): 0: 611: 44.87
+	Mm
		1141851 MEF2A_MOUSE (1-498): 7.41e-86: 275: 100.00		HDAC4_MOUSE (33-921): 0: 611: 44.87
+	Hs
		880693 MEF2C_HUMAN (1-498): 7.03e-88: 279: 58.15		HDAC4_HUMAN (33-921): 0: 599: 45.85
+	Hs
		880686 MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96		HDAC4_HUMAN (33-921): 0: 599: 45.85
+	Hs
		987233 MEF2C_HUMAN (1-498): 7.03e-88: 279: 58.15		HDAC9_HUMAN (33-879): 0: 582: 41.17
+	Hs
		968804 MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96		HDAC9_HUMAN (33-879): 0: 582: 41.17
+	Hs
		880729 MEF2D_HUMAN (1-496): 4.69e-72: 239: 50.37		HDAC4_HUMAN (33-921): 0: 599: 45.85
+	Mm
		1112770 MEF2C_MOUSE (1-498): 5.43e-89: 282: 57.96		Q3UJF1_MOUSE (33-936): 0: 555: 39.59
+	Mm
		1112756 MEF2A_MOUSE (1-498): 7.41e-86: 275: 100.00		Q3UJF1_MOUSE (33-936): 0: 555: 39.59
+	Hs
		987234 MEF2C_HUMAN (1-498): 7.03e-88: 279: 58.15		HDAC5_HUMAN (33-936): 7.02e-179: 550: 39.40
+	Hs
		968805 MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96		HDAC5_HUMAN (33-936): 7.02e-179: 550: 39.40
+	Hs
		1059602 MEF2D_HUMAN (1-496): 4.69e-72: 239: 50.37		HDAC5_HUMAN (33-936): 7.02e-179: 550: 39.40
+	Hs
		968777 MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96		HDAC1_HUMAN (497-930): 1.72e-160: 481: 20.62
+	Hs
		1038381 MEF2D_HUMAN (1-496): 4.69e-72: 239: 50.37		HDAC1_HUMAN (497-930): 1.72e-160: 481: 20.62
+	Hs
		177265 MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96		HDAC3_HUMAN (503-926): 7.5e-149: 449: 19.01
+	Hs
		177297 MEF2D_HUMAN (1-496): 4.69e-72: 239: 50.37		HDAC3_HUMAN (503-926): 7.5e-149: 449: 19.01
+	Mm
		292416 MEF2D_MOUSE (1-496): 7.35e-71: 236: 50.47		HDAC3_MOUSE (503-926): 5.1e-149: 449: 19.01