HitPredict

Interactor 1: MYH9 (P35579)
Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)
Gene: MYH9

Interactor 2: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26496610, 37071682, 35575683, 38334954, 24981860, 36929633, 35235311, 36652389
Identification Methods affinity chromatography technology, cross-linking study, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains IQ~Myosin_head, Myosin_head~Myosin_head, Myosin_N~Myosin_head, Myosin_head~Myosin_tail_1, Myosin_N~Myosin_tail_1, Myosin_tail_1~Myosin_tail_1
Common GO terms GO:0000146 - microfilament motor activity
GO:0001618 - virus receptor activity
GO:0001701 - in utero embryonic development
GO:0001725 - stress fiber
GO:0001778 - plasma membrane repair
and 23 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1960
Hs

1 1976
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Last updated: 11Aug2025