HitPredict

Interactor 1: Q60I23 (Q60I23)
SRY (sex determining region Y)-box 2 (Sox2 protein) (Transcriptional factor SOX2)
Gene: Sox2

Interactor 2: SMRC2 (Q6PDG5)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: Smarcc2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	21532573
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045597 - positive regulation of cell differentiation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 319 Mm			1 1213
+	Hs
		818277 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		SMRC2_HUMAN (1-1202): 0: 1027: 96.18
+	Hs
		818323 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		SMRC1_HUMAN (4-1094): 0: 984: 60.90
+	Mm
		956815 Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00		SMRC1_MOUSE (4-1108): 0: 963: 60.94
+	Mm
		818694 SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43		SMRC1_MOUSE (4-1108): 0: 963: 60.94
+	Hs
		818822 SOX9_HUMAN (27-262): 3.13e-35: 135: 27.24		SMRC2_HUMAN (1-1202): 0: 1027: 96.18
+	Hs
		1272921 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		SMRC1_HUMAN (4-1094): 0: 984: 60.90
+	Mm
		101612 Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00		F8VQL9_MOUSE (545-1206): 1.07e-38: 160: 12.56
+	Hs
		818668 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		NCOR2_HUMAN (545-1199): 2.9e-37: 155: 11.34
+	Hs
		261435 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		NCOR1_HUMAN (545-1142): 9.92e-29: 127: 10.61
+	Hs
		727832 SOX5_HUMAN (17-129): 1.06e-39: 150: 40.71		NCOR2_HUMAN (545-1199): 2.9e-37: 155: 11.34
+	Hs
		225812 SOX15_HUMAN (13-179): 7.82e-39: 138: 47.93		NCOR2_HUMAN (545-1199): 2.9e-37: 155: 11.34
+	Hs
		261421 SOX5_HUMAN (17-129): 1.06e-39: 150: 40.71		NCOR1_HUMAN (545-1142): 9.92e-29: 127: 10.61
+	Hs
		818550 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		CHD7_HUMAN (843-1213): 3.97e-11: 70.1: 11.54
+	Mm
		57186 Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00		CHD7_MOUSE (864-1213): 3.7e-09: 63.5: 11.41
+	Hs
		818266 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		KMT2C_HUMAN (656-1210): 1.3e-09: 65: 11.00
+	Hs
		727814 SOX5_HUMAN (17-129): 1.06e-39: 150: 40.71		CHD7_HUMAN (843-1213): 3.97e-11: 70.1: 11.54
+	Hs
		1300971 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		CHD7_HUMAN (843-1213): 3.97e-11: 70.1: 11.54
+	Hs
		867119 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		SC24C_HUMAN (928-1213): 3.84e-10: 66.6: 18.09
+	Hs
		818819 SOX9_HUMAN (27-262): 3.13e-35: 135: 27.24		KMT2C_HUMAN (656-1210): 1.3e-09: 65: 11.00
+	Hs
		818828 SOX9_HUMAN (27-262): 3.13e-35: 135: 27.24		CBP_HUMAN (725-1209): 1.33e-09: 65: 11.94