HitPredict

Interactor 1: Q60I23 (Q60I23)
SRY (sex determining region Y)-box 2 (Sox2 protein) (Transcriptional factor SOX2)
Gene: Sox2

Interactor 2: MTREX (Q9CZU3)
Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase)
Gene: MTREX

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21532573
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 319 Mm			1 1040
+	Hs
		786907 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		MTREX_HUMAN (1-1040): 0: 887: 97.31
+	Hs
		331739 NSD2_HUMAN (1-250): 1.25e-27: 115: 11.83		MTREX_HUMAN (1-1040): 0: 887: 97.31
+	Hs
		818246 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		ASCC3_HUMAN (24-811): 1.47e-95: 336: 15.67
+	Hs
		571352 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		DDX5_HUMAN (22-567): 8.56e-97: 321: 11.07
+	Mm
		818738 SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43		Q8BTS0_MOUSE (19-567): 1.42e-96: 320: 11.19
+	Mm
		1142014 Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00		SMCA5_MOUSE (11-860): 4.88e-89: 310: 11.67
+	Hs
		818320 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		DDX17_HUMAN (54-566): 1.62e-91: 310: 10.65
+	Mm
		818707 SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43		DDX17_MOUSE (45-566): 4.75e-92: 309: 10.48
+	Hs
		229339 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		SMCA5_HUMAN (13-860): 8.99e-88: 306: 11.69
+	Hs
		272250 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		U520_HUMAN (111-841): 2.84e-102: 356: 17.28
+	Hs
		272110 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		U520_HUMAN (111-841): 2.84e-102: 356: 17.28
+	Hs
		571557 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		DDX5_HUMAN (22-567): 8.56e-97: 321: 11.07
+	Hs
		1271630 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		DDX17_HUMAN (54-566): 1.62e-91: 310: 10.65
+	Hs
		229467 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		SMCA5_HUMAN (13-860): 8.99e-88: 306: 11.69
+	Hs
		571415 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		DDX5_HUMAN (22-567): 8.56e-97: 321: 11.07
+	Hs
		996809 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		DDX17_HUMAN (54-566): 1.62e-91: 310: 10.65
+	Hs
		229376 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		SMCA5_HUMAN (13-860): 8.99e-88: 306: 11.69
+	Hs
		229270 NSD2_HUMAN (1-250): 1.25e-27: 115: 11.83		SMCA5_HUMAN (13-860): 8.99e-88: 306: 11.69