Interactor 1: M3K7 (Q62073)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: Map3k7

Interactor 2: M3K7 (Q62073)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: Map3k7

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 18635759, 17384642, 16301747
Identification Methods affinity chromatography technology, protein kinase assay
Interaction Type physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0000165 - MAPK cascade
GO:0000287 - magnesium ion binding
GO:0001223 - transcription coactivator binding
GO:0001525 - angiogenesis
GO:0001649 - osteoblast differentiation
and 44 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 579
Mm

1 579
+ Hs
+ At
+ At
+ At
+ At
+ At
+ At
+ Dm
+ Hs
+ Zm
+ At
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024