Interactor 1: SH3G2 (Q62420)
Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4)
Gene: Sh3gl2

Interactor 2: PRKN (Q9WVS6)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.59 1.00 0.770

The method score is based on:

Property Details
Experiments 20064468
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, enzymatic study
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_1~ubiquitin
Common GO terms GO:0005737 - cytoplasm
GO:0019901 - protein kinase binding
GO:0030672 - synaptic vesicle membrane
GO:0043025 - neuronal cell body
GO:0045202 - synapse
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 352
Mm

1 464
+ Mm
+ Hs
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+ Hs
+ Hs
+ Hs
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+ Rn
+ Rn
+ Mm
+ Rn
+ Xl
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024