Protein: MTCL3
Microtubule cross-linking factor 3

Gene: MTCL3
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q5TF21

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0010506 - regulation of autophagy
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1216317

SCN3B
Sodium channel regulatory subunit beta-3

2

4

High-throughput

0.628

High

717846

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

5

High-throughput

0.601

High

1216299

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.513

High

1216302

MCLN2
Mucolipin-2

1

0

High-throughput

0.513

High

436682

KPCB
Protein kinase C beta type

1

15

High-throughput

0.489

High

991199

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

6

High-throughput

0.489

High

1143887

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

1

4

High-throughput

0.489

High

1143927

2A5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

1

4

High-throughput

0.489

High

1158052

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

4

High-throughput

0.489

High

1204361

SGO1
Shugoshin 1

1

1

High-throughput

0.489

High

1210041

A20A2
Putative ankyrin repeat domain-containing protein 20A2

1

8

High-throughput

0.489

High

1216296

A20A1
Ankyrin repeat domain-containing protein 20A1

1

8

High-throughput

0.489

High

1216297

CYTSA
Cytospin-A

1

19

High-throughput

0.489

High

1216300

TLK2
Serine/threonine-protein kinase tousled-like 2

1

20

High-throughput

0.489

High

1216303

ZN276
Zinc finger protein 276

1

14

High-throughput

0.489

High

1216304

B3GN7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

1

1

High-throughput

0.489

High

1216309

EFHD1
EF-hand domain-containing protein D1

1

14

High-throughput

0.489

High

1216310

RIOK2
Serine/threonine-protein kinase RIO2

1

2

High-throughput

0.489

High

1216312

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

7

High-throughput

0.489

High

1216313

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

15

High-throughput

0.489

High

1216314

RTN4
Reticulon-4

1

3

High-throughput

0.489

High

1216319

ZN214
Zinc finger protein 214

1

7

High-throughput

0.489

High

947208

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

4

High-throughput

0.479

High

1140400

KIF14
Kinesin-like protein KIF14

1

16

High-throughput

0.479

High

1191420

GRDN
Girdin

1

17

High-throughput

0.479

High

529947

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.445

High

1216311

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

1

High-throughput

0.445

High

106086

APRIO
Alternative prion protein

1

13

High-throughput

0.437

High

412069

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.437

High

920027

PLK1
Serine/threonine-protein kinase PLK1

1

5

High-throughput

0.437

High

1015233

ERH
Enhancer of rudimentary homolog

1

1

High-throughput

0.437

High

1216298

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

250935

TPST1
Protein-tyrosine sulfotransferase 1

1

0

High-throughput

0.426

High

1216305

MIPT3
TRAF3-interacting protein 1

1

5

High-throughput

0.417

High

1216316

DISC1
Disrupted in schizophrenia 1 protein

1

9

High-throughput

0.417

High

1216318

TNIK
TRAF2 and NCK-interacting protein kinase

1

20

High-throughput

0.417

High

255065

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

6

High-throughput

0.407

High

934724

TERA
Transitional endoplasmic reticulum ATPase

1

8

High-throughput

0.407

High

1216301

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

10

High-throughput

0.407

High

1216307

CEP63
Centrosomal protein of 63 kDa

1

18

High-throughput

0.407

High

1216308

CK5P2
CDK5 regulatory subunit-associated protein 2

1

19

High-throughput

0.407

High

1216306

NRBF2
Nuclear receptor-binding factor 2

3

0

High-throughput

0.347

High

1027039

REEP5
Receptor expression-enhancing protein 5

2

0

High-throughput

0.328

High

867792

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.279

Low

1216315

TSSP
Thymus-specific serine protease

1

0

High-throughput

0.279

Low

1032008

TFAP4
Transcription factor AP-4

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025