HitPredict

Interactor 1: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 25416956, 23555304, 16189514, 21516116, 37071682, 25253489, 31839598, 21988832, 16148043, 22416126
Identification Methods two hybrid, cross-linking study, two hybrid array, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains NOPS~NOPS, NOPS~RRM_1, RRM_1~RRM_1
Common GO terms GO:0001650 - fibrillar center
GO:0002218 - activation of innate immune response
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0003723 - RNA binding
and 21 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 11Aug2025