Protein: NONO
Non-POU domain-containing octamer-binding protein (NonO protein)

Gene: NONO
Organism: Mus musculus
Interactions: 47
UniProt ID: Q99K48

Gene Ontology (top 5):
GO:0001650 - fibrillar center
GO:0002218 - activation of innate immune response
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1021185

UHMK1
Serine/threonine-protein kinase Kist

1

20

Small-scale

0.713

High

988251

TRA2B
Transformer-2 protein homolog beta

1

19

High-throughput

0.621

High

1222970

EWS
RNA-binding protein EWS

1

20

High-throughput

0.621

High

1238932

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

20

High-throughput

0.621

High

1298130

RBM4
RNA-binding protein 4

1

18

High-throughput

0.621

High

1341539

PSPC1
Paraspeckle component 1

1

17

High-throughput

0.621

High

1408761

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

5

High-throughput

0.621

High

1354144

SFPQ
Splicing factor, proline- and glutamine-rich

1

18

Small-scale

0.618

High

1000191

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

16

High-throughput

0.555

High

1298116

CSTFT
Cleavage stimulation factor subunit 2 tau variant

1

19

High-throughput

0.555

High

604527

SPI1
Transcription factor PU.1

1

5

Small-scale

0.515

High

397

AUTS2
Autism susceptibility gene 2 protein homolog

1

8

Small-scale

0.500

High

993857

UBC9
SUMO-conjugating enzyme UBC9

1

6

High-throughput

0.481

High

1204349

NUFP2
FMR1-interacting protein NUFIP2

1

6

High-throughput

0.481

High

205754

PER1
Period circadian protein homolog 1

1

8

Small-scale

0.479

High

236763

PER2
Period circadian protein homolog 2

1

8

Small-scale

0.479

High

373706

MYC
Myc proto-oncogene protein

1

20

Small-scale

0.479

High

542883

RARA
Retinoic acid receptor alpha

1

20

Small-scale

0.479

High

586145

TFE2
Transcription factor E2-alpha

1

3

High-throughput

0.479

High

629425

PO5F1
POU domain, class 5, transcription factor 1

1

6

High-throughput

0.479

High

927980

ATX1
Ataxin-1

1

5

High-throughput

0.479

High

966070

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

20

High-throughput

0.479

High

972304

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.479

High

1189471

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

Small-scale

0.479

High

1191180

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

6

High-throughput

0.479

High

1225226

TFE3
Transcription factor E3

1

11

High-throughput

0.479

High

1231595

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

20

Small-scale

0.479

High

1282422

FACD2
Fanconi anemia group D2 protein homolog

1

9

High-throughput

0.479

High

1283174

NANOG
Homeobox protein NANOG

1

10

High-throughput

0.479

High

1298638

KAT5
Histone acetyltransferase KAT5

1

5

Small-scale

0.479

High

1317309

PPHLN
Periphilin-1

1

3

Small-scale

0.479

High

1362590

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

1408762

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

3

Small-scale

0.479

High

1408763

FZR1
Fizzy-related protein homolog

1

20

High-throughput

0.479

High

988910

RAC1
Ras-related C3 botulinum toxin substrate 1

1

3

High-throughput

0.457

High

977660

RL18A
Large ribosomal subunit protein eL20

1

1

High-throughput

0.439

High

1222383

MARE1
Microtubule-associated protein RP/EB family member 1

1

2

High-throughput

0.439

High

398900

CFAD
Complement factor D

1

5

High-throughput

0.437

High

1222508

SAP
Prosaposin

1

1

High-throughput

0.437

High

1233057

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

High-throughput

0.437

High

1297795

A16L1
Autophagy-related protein 16-1

1

18

High-throughput

0.437

High

1298327

MT21E
Protein-lysine methyltransferase METTL21E

1

9

High-throughput

0.437

High

1298695

TTC23
Tetratricopeptide repeat protein 23

1

1

High-throughput

0.437

High

1317587

FNDC5
Fibronectin type III domain-containing protein 5

1

4

High-throughput

0.437

High

1341432

BFAR
Bifunctional apoptosis regulator

1

20

Small-scale

0.437

High

97983

RYR2
Ryanodine receptor 2

1

9

High-throughput

0.407

High

59852

CMAP2
Ciliary microtubule-associated protein 2

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025