HitPredict

Interactor 1: PHC1 (Q64028)
Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28)
Gene: PHC1

Interactor 2: SCMH1 (Q8K214)
Polycomb protein SCMH1 (Sex comb on midleg homolog 1)
Gene: SCMH1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10653359
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SAM_1~SAM_1
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0042393 - histone binding GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1010 Mm			1 706
+	Hs
		943082 PHC1_HUMAN (1-1010): 7.84e-87: 303: 91.98		SCMH1_HUMAN (1-664): 0: 837: 92.63
+	Hs
		1292157 SMBT1_HUMAN (832-1008): 6.34e-36: 149: 28.57		SCMH1_HUMAN (1-664): 0: 837: 92.63
+	Mm
		1144864 PHC1_MOUSE (1-1010): 6.25e-90: 311: 100.00		PHC2_MOUSE (212-660): 6.49e-90: 300: 20.13
+	Hs
		943073 PHC1_HUMAN (1-1010): 7.84e-87: 303: 91.98		PHC2_HUMAN (231-660): 6.63e-79: 271: 19.19
+	Dm
		1341976 Q9NF31_DROME (412-1009): 8.58e-50: 194: 21.33		SCM_DROME (19-659): 5.81e-115: 368: 30.92
+	Hs
		943059 PHC1_HUMAN (1-1010): 7.84e-87: 303: 91.98		PHC1_HUMAN (267-661): 8.77e-57: 210: 18.63
+	Hs
		1123979 Q59GP6_HUMAN (1-1010): 3.27e-86: 302: 91.98		Q59GP6_HUMAN (267-661): 1.16e-55: 208: 18.63
+	Mm
		1144856 PHC1_MOUSE (1-1010): 6.25e-90: 311: 100.00		PHC1_MOUSE (234-661): 2.39e-46: 179: 15.25
+	Hs
		943067 PHC1_HUMAN (1-1010): 7.84e-87: 303: 91.98		SMBT2_HUMAN (22-505): 5.09e-47: 181: 17.78
+	Hs
		943081 PHC1_HUMAN (1-1010): 7.84e-87: 303: 91.98		LMBL2_HUMAN (1-315): 1.39e-45: 175: 19.09
+	Hs
		943078 PHC1_HUMAN (1-1010): 7.84e-87: 303: 91.98		PHC3_HUMAN (263-661): 7.5e-44: 171: 19.56
+	Hs
		943098 PHC1_HUMAN (1-1010): 7.84e-87: 303: 91.98		SCML1_HUMAN (490-663): 7e-29: 119: 28.93
+	Hs
		1220902 SMBT1_HUMAN (832-1008): 6.34e-36: 149: 28.57		PHC2_HUMAN (231-660): 6.63e-79: 271: 19.19
+	Hs
		943097 PHC1_HUMAN (1-1010): 7.84e-87: 303: 91.98		SMBT1_HUMAN (127-275): 1.98e-17: 88.7: 24.50
+	Dm
		1341978 Q9NF31_DROME (412-1009): 8.58e-50: 194: 21.33		SMBT_DROME (2-331): 1.2e-40: 162: 19.00
+	Dm
		764508 Q9NF31_DROME (412-1009): 8.58e-50: 194: 21.33		PHP_DROME (388-662): 3.75e-35: 145: 20.00
+	Hs
		1295449 SMBT1_HUMAN (832-1008): 6.34e-36: 149: 28.57		LMBL3_HUMAN (2-127): 5.34e-29: 125: 33.11
+	Hs
		1139331 SMBT1_HUMAN (832-1008): 6.34e-36: 149: 28.57		SAM13_HUMAN (548-668): 1.58e-29: 115: 31.50
+	Hs
		1164476 SMBT1_HUMAN (832-1008): 6.34e-36: 149: 28.57		SAMD1_HUMAN (330-667): 7.31e-25: 111: 18.16