Protein: RABE2
Rab GTPase-binding effector protein 2 (Rabaptin-5beta)

Gene: RABE2, RABEP2
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q9H5N1

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005769 - early endosome
GO:0005794 - Golgi apparatus
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1434693

RABX5
Rab5 GDP/GTP exchange factor

3

6

High-throughput

0.855

High

630972

RAB4A
Ras-related protein Rab-4A

2

10

High-throughput

0.793

High

1144878

RABE1
Rab GTPase-binding effector protein 1

2

19

Small-scale

0.776

High

1399424

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

3

High-throughput

0.691

High

508629

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

4

12

High-throughput

0.686

High

1434686

EXOC1
Exocyst complex component 1

3

1

High-throughput

0.675

High

1434688

IFT57
Intraflagellar transport protein 57 homolog

4

0

High-throughput

0.661

High

631477

RAB5A
Ras-related protein Rab-5A

1

10

Small-scale

0.647

High

1060575

KLC1
Kinesin light chain 1

2

2

High-throughput

0.628

High

1382584

EXOC4
Exocyst complex component 4

2

1

High-throughput

0.628

High

1434680

ASB7
Ankyrin repeat and SOCS box protein 7

2

7

High-throughput

0.628

High

325407

DIRA1
GTP-binding protein Di-Ras1

1

11

High-throughput

0.618

High

1286589

SDCG8
Serologically defined colon cancer antigen 8

2

19

Small-scale

0.618

High

1434679

RABE2
Rab GTPase-binding effector protein 2

1

16

High-throughput

0.618

High

1390819

CPNE2
Copine-2

3

5

High-throughput

0.604

High

1434691

ZRAN1
Ubiquitin thioesterase ZRANB1

2

9

High-throughput

0.584

High

1382032

CPNE4
Copine-4

2

5

High-throughput

0.574

High

1396450

F167A
Protein FAM167A

2

2

High-throughput

0.574

High

1434682

CPNE5
Copine-5

2

5

High-throughput

0.574

High

228629

STRN
Striatin

1

13

High-throughput

0.536

High

324213

CE152
Centrosomal protein of 152 kDa

1

18

High-throughput

0.536

High

718630

CDC27
Cell division cycle protein 27 homolog

1

4

High-throughput

0.536

High

721067

CLIP1
CAP-Gly domain-containing linker protein 1

1

16

High-throughput

0.536

High

1029758

FOXK2
Forkhead box protein K2

1

5

High-throughput

0.536

High

1087034

KIF5A
Kinesin heavy chain isoform 5A

1

4

High-throughput

0.536

High

1092929

STRN3
Striatin-3

1

18

High-throughput

0.536

High

1093050

CDC16
Cell division cycle protein 16 homolog

1

4

High-throughput

0.536

High

1135382

SLMAP
Sarcolemmal membrane-associated protein

1

20

High-throughput

0.536

High

1146827

PCBP1
Poly(rC)-binding protein 1

1

5

High-throughput

0.536

High

1217358

STRP1
Striatin-interacting protein 1

1

1

High-throughput

0.536

High

1226596

MAP1S
Microtubule-associated protein 1S

1

7

High-throughput

0.536

High

1248197

SAS6
Spindle assembly abnormal protein 6 homolog

1

18

High-throughput

0.536

High

1295215

HOME1
Homer protein homolog 1

1

15

High-throughput

0.536

High

1312880

KLHL7
Kelch-like protein 7

1

3

High-throughput

0.536

High

1401165

SPAG5
Sperm-associated antigen 5

1

18

High-throughput

0.536

High

1406383

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

20

High-throughput

0.536

High

1411925

SIKE1
Suppressor of IKBKE 1

1

2

High-throughput

0.536

High

1419857

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

15

High-throughput

0.536

High

1429705

KLC2
Kinesin light chain 2

1

4

High-throughput

0.536

High

1434681

TRI45
E3 ubiquitin-protein ligase TRIM45

1

17

High-throughput

0.536

High

1434684

SHLB2
Endophilin-B2

1

9

High-throughput

0.536

High

1434687

FGOP2
FGFR1 oncogene partner 2

1

2

High-throughput

0.536

High

1434696

PHOCN
MOB-like protein phocein

1

2

High-throughput

0.536

High

252917

EXOC3
Exocyst complex component 3

1

0

High-throughput

0.513

High

911874

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

0

High-throughput

0.513

High

1244533

SHQ1
Protein SHQ1 homolog

1

0

High-throughput

0.513

High

1251842

PPR21
Protein phosphatase 1 regulatory subunit 21

1

0

High-throughput

0.513

High

1310056

DEN6A
Protein DENND6A

1

0

High-throughput

0.513

High

1313697

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.513

High

1333499

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.513

High

1434695

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.513

High

132299

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

Small-scale

0.501

High

1098845

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

18

Small-scale

0.501

High

107340

F8VWT9
HECT domain E3 ubiquitin protein ligase 4

1

6

High-throughput

0.489

High

1017491

FOXK1
Forkhead box protein K1

1

6

High-throughput

0.489

High

1179856

INSY1
Inhibitory synaptic factor 1

1

1

High-throughput

0.489

High

1254050

R9BP
Regulator of G-protein signaling 9-binding protein

1

1

High-throughput

0.489

High

1287445

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

8

High-throughput

0.489

High

1315993

NRSN1
Neurensin-1

1

1

High-throughput

0.489

High

1399059

TMM74
Transmembrane protein 74

1

1

High-throughput

0.489

High

1401020

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

12

High-throughput

0.489

High

1434685

STRN4
Striatin-4

1

12

High-throughput

0.489

High

1323345

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

3

High-throughput

0.481

High

412613

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

700735

PSA5
Proteasome subunit alpha type-5

1

2

Small-scale

0.479

High

831429

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

1338373

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

1434692

UBQL2
Ubiquilin-2

1

2

High-throughput

0.479

High

1434694

AT11B
Phospholipid-transporting ATPase IF

1

2

High-throughput

0.479

High

1369286

FRAT1
Proto-oncogene FRAT1

1

0

High-throughput

0.460

High

1382499

TM230
Transmembrane protein 230

1

0

High-throughput

0.458

High

1349765

FBX25
F-box only protein 25

1

9

Small-scale

0.457

High

1352985

CE192
Centrosomal protein of 192 kDa

1

1

High-throughput

0.445

High

658835

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

7

High-throughput

0.437

High

1255543

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.437

High

1434683

Q9HCK3
KIAA1569 protein

1

1

High-throughput

0.437

High

1434689

KS6B2
Ribosomal protein S6 kinase beta-2

1

10

High-throughput

0.437

High

1273804

NIPA1
Magnesium transporter NIPA1

1

0

High-throughput

0.426

High

1010532

EREP3
Protein ENTREP3

1

0

High-throughput

0.279

Low

1254146

CA122
Uncharacterized protein C1orf122

1

0

High-throughput

0.279

Low

1397838

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.279

Low

1415076

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.279

Low

1434690

CS025
UPF0449 protein C19orf25

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025