HitPredict

Interactor 1: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tubulin~fn3
Common GO terms	GO:0005886 - plasma membrane GO:0031594 - neuromuscular junction GO:0051402 - neuron apoptotic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 998 Hs			1 451
+	Hs
		996958 EPHA7_HUMAN (1-998): 0: 1312: 100.00		TBA4A_HUMAN (1-450): 0: 714: 96.00
+	Hs
		457456 EPHA7_HUMAN (1-998): 0: 1312: 100.00		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		457332 EPHA4_HUMAN (4-998): 0: 1233: 62.29		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		932054 EPHA4_HUMAN (4-998): 0: 1233: 62.29		TBB4B_HUMAN (1-437): 0: 694: 40.50
+	Hs
		710806 EPHB2_HUMAN (32-995): 0: 1192: 57.51		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		710166 EPHA2_HUMAN (29-998): 0: 1085: 50.36		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		931935 EPHB4_HUMAN (18-989): 0: 1036: 48.58		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		439763 INSR_HUMAN (284-953): 3.53e-145: 469: 24.57		TBA1A_HUMAN (1-451): 0: 710: 100.00
+	Hs
		439616 INSR_HUMAN (284-953): 3.53e-145: 469: 24.57		TBB5_HUMAN (1-439): 0: 696: 40.77