HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Tubulin~fn3
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 976 Hs			1 451
+	Hs
		996958 EPHA7_HUMAN (4-974): 0: 1120: 50.15		TBA4A_HUMAN (1-450): 0: 716: 96.44
+	Hs
		1147355 EPHA7_HUMAN (4-974): 0: 1120: 50.15		TBA1A_HUMAN (1-440): 0: 712: 99.55
+	Hs
		457456 EPHA7_HUMAN (4-974): 0: 1120: 50.15		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		457332 EPHA4_HUMAN (1-974): 0: 1110: 50.35		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		932054 EPHA4_HUMAN (1-974): 0: 1110: 50.35		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		710806 EPHB2_HUMAN (28-973): 0: 1077: 48.29		TBA1B_HUMAN (1-440): 0: 714: 100.00
+	Hs
		931935 EPHB4_HUMAN (14-970): 0: 974: 44.99		TBA1B_HUMAN (1-440): 0: 714: 100.00
+	Hs
		439763 INSR_HUMAN (281-911): 2.91e-136: 444: 24.78		TBA1A_HUMAN (1-440): 0: 712: 99.55
+	Rn
		580523 INSR_RAT (371-873): 1.87e-134: 440: 29.49		TBA4A_RAT (1-450): 0: 716: 96.44
+	Hs
		465482 IGF1R_HUMAN (393-877): 1.45e-133: 437: 29.90		TBA4A_HUMAN (1-450): 0: 716: 96.44
+	Hs
		439616 INSR_HUMAN (281-911): 2.91e-136: 444: 24.78		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		463606 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		TBA1A_HUMAN (1-440): 0: 712: 99.55