Interactor 1: Q69FE3 (Q69FE3)
Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)
Gene: IRAK4

Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 25416956
Identification Methods two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005149 - interleukin-1 receptor binding
GO:0005737 - cytoplasm
GO:0007254 - JNK cascade
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0045087 - innate immune response
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 460
Hs

1 296
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Last updated: 15 Jul 2024