Interactor 1: Q69FE3 (Q69FE3)
Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)
Gene: IRAK4
Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.44 | 0.60 | 0.515 |
The method score is based on:
Property | Details |
---|---|
Experiments | 25416956 |
Identification Methods | two hybrid prey pooling approach, two hybrid array, validated two hybrid |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005149 - interleukin-1 receptor binding GO:0005737 - cytoplasm GO:0007254 - JNK cascade GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0045087 - innate immune response and 1 others more... |
Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024