HitPredict

Interactor 1: PDS5A (Q6A026)
Sister chromatid cohesion protein PDS5 homolog A
Gene: PDS5A

Interactor 2: SMC1A (Q9CU62)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Chromosome segregation protein SmcB) (Sb1.8)
Gene: SMC1A

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33760811
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006281 - DNA repair GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1332 Mm			1 1233
+	Mm
		93884 E9QPI5_MOUSE (1-1332): 0: 1769: 99.70		SMC1A_MOUSE (1-1233): 5.26e-126: 420: 100.00
+	Hs
		1057273 PDS5A_HUMAN (1-1332): 0: 1739: 97.53		SMC1A_HUMAN (1-1233): 1.18e-125: 419: 99.84
+	Xl
		292730 PD5AA_XENLA (1-1332): 0: 1628: 86.27		SMC1A_XENLA (1-1232): 1.2e-119: 402: 93.99
+	Xl
		292729 PD5AB_XENLA (1-1332): 0: 1625: 86.41		SMC1A_XENLA (1-1232): 1.2e-119: 402: 93.99
+	Mm
		93885 E9QPI5_MOUSE (1-1332): 0: 1769: 99.70		SMC3_MOUSE (3-1229): 7.9e-70: 258: 16.17
+	Hs
		1100586 PDS5A_HUMAN (1-1332): 0: 1739: 97.53		SMC3_HUMAN (3-1229): 1.16e-69: 258: 16.17
+	Hs
		1057405 PDS5B_HUMAN (11-1286): 0: 1523: 69.23		SMC1A_HUMAN (1-1233): 1.18e-125: 419: 99.84
+	Mm
		1118817 PDS5B_MOUSE (11-1286): 0: 1520: 69.34		SMC1A_MOUSE (1-1233): 5.26e-126: 420: 100.00
+	Xl
		292728 PD5BA_XENLA (11-1297): 0: 1503: 68.13		SMC1A_XENLA (1-1232): 1.2e-119: 402: 93.99
+	Xl
		292739 PD5AA_XENLA (1-1332): 0: 1628: 86.27		SMC3_XENLA (3-1229): 1.8e-71: 263: 16.27
+	Xl
		1117310 PD5AB_XENLA (1-1332): 0: 1625: 86.41		Q8AW91_XENLA (3-1229): 3.98e-69: 256: 15.90
+	Xl
		292740 PD5BB_XENLA (11-1297): 0: 1527: 68.61		SMC3_XENLA (3-1229): 1.8e-71: 263: 16.27
+	Hs
		1345702 PDS5B_HUMAN (11-1286): 0: 1523: 69.23		SMC3_HUMAN (3-1229): 1.16e-69: 258: 16.17
+	Xl
		292738 PD5BA_XENLA (11-1297): 0: 1503: 68.13		SMC3_XENLA (3-1229): 1.8e-71: 263: 16.27
+	Xl
		1115499 PD5BA_XENLA (11-1297): 0: 1503: 68.13		Q8AW91_XENLA (3-1229): 3.98e-69: 256: 15.90
+	Sp
		293288 PDS5_SCHPO (33-1158): 0: 896: 21.92		SMC1_SCHPO (1-1225): 3.48e-71: 262: 32.77
+	Sp
		193880 PDS5_SCHPO (33-1158): 0: 896: 21.92		SMC3_SCHPO (3-1225): 1.24e-65: 245: 17.18
+	Sc
		810772 PDS5_YEAST (35-1144): 0: 838: 19.72		SMC3_YEAST (3-1215): 8.01e-78: 283: 18.28
+	Sc
		700799 PDS5_YEAST (35-1144): 0: 838: 19.72		SMC1_YEAST (1-1225): 8.93e-70: 258: 26.70
+	Hs
		69118 A9IYQ1_HUMAN (1056-1286): 9.65e-54: 192: 37.22		SMC1A_HUMAN (1-1233): 1.18e-125: 419: 99.84