HitPredict

Interactor 1: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Interactor 2: PP4P1 (Q86T03)
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 1 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase I) (Transmembrane protein 55B)
Gene: PIP4P1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.55 0.628

The method score is based on:

Property Details
Experiments 35271311, 34079125, 36476874
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0031902 - late endosome membrane
GO:0032418 - lysosome localization
GO:1904263 - positive regulation of TORC1 signaling
Homologous interactions 0

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Last updated: 15 Jul 2024