HitPredict

Interactor 1: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.753

Property	Details
Experiments	25416956, 29162697, 26186194, 26496610, 28514442, 33961781, 35271311, 31515488
Identification Methods	two hybrid, affinity chromatography technology, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005813 - centrosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 268 Hs			1 2346
+	Hs
		1218041 MARE3_HUMAN (1-268): 1.92e-134: 382: 63.70		MYOME_HUMAN (1-2346): 0: 679: 100.00
+	Hs
		1134592 MARE1_HUMAN (1-257): 3.34e-150: 421: 100.00		NUMA1_HUMAN (1-1306): 3.35e-47: 189: 11.77
+	Hs
		176987 MARE1_HUMAN (1-257): 3.34e-150: 421: 100.00		CE290_HUMAN (874-2329): 3.16e-28: 127: 9.32
+	Hs
		883963 MARE3_HUMAN (1-268): 1.92e-134: 382: 63.70		CENPF_HUMAN (901-2161): 3.62e-35: 150: 9.01
+	Hs
		1152234 MARE1_HUMAN (1-257): 3.34e-150: 421: 100.00		CP250_HUMAN (1523-2339): 1.05e-13: 79.7: 11.26
+	Hs
		1035508 MARE1_HUMAN (1-257): 3.34e-150: 421: 100.00		CENPE_HUMAN (1535-2336): 3.63e-13: 78.1: 10.44
+	Hs
		1152214 MARE1_HUMAN (1-257): 3.34e-150: 421: 100.00		CK5P2_HUMAN (434-1035): 2.54e-11: 71.9: 10.82
+	Hs
		587675 MARE1_HUMAN (1-257): 3.34e-150: 421: 100.00		DESP_HUMAN (6-681): 6.11e-10: 67.4: 20.72
+	Hs
		1402929 MARE3_HUMAN (1-268): 1.92e-134: 382: 63.70		CK5P2_HUMAN (434-1035): 2.54e-11: 71.9: 10.82