Protein: MYOME
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)

Gene: MYOME, PDE4DIP
Organism: Homo sapiens
Interactions: 233
UniProt ID: Q5VU43

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005813 - centrosome
GO:0007098 - centrosome cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1217997

CK5P2
CDK5 regulatory subunit-associated protein 2

4

19

Small-scale

0.881

High

1217953

MYOME
Myomegalin

2

19

High-throughput

0.789

High

1152100

MARE1
Microtubule-associated protein RP/EB family member 1

8

9

Small-scale

0.753

High

651670

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

6

18

Small-scale

0.736

High

725507

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

6

10

Small-scale

0.732

High

605714

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

5

19

Small-scale

0.718

High

833638

NAA10
N-alpha-acetyltransferase 10

5

1

High-throughput

0.715

High

991566

DYL1
Dynein light chain 1, cytoplasmic

5

7

Small-scale

0.709

High

140307

SDCB1
Syntenin-1

4

1

High-throughput

0.698

High

1218041

MARE3
Microtubule-associated protein RP/EB family member 3

4

9

High-throughput

0.692

High

1218031

ZN581
Zinc finger protein 581

3

2

High-throughput

0.675

High

946139

MLF1
Myeloid leukemia factor 1

3

1

High-throughput

0.656

High

1218003

AKAP9
A-kinase anchor protein 9

3

19

Small-scale

0.656

High

1217967

CC146
Coiled-coil domain-containing protein 146

3

19

High-throughput

0.654

High

1217981

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

3

0

High-throughput

0.654

High

877143

KC1D
Casein kinase I isoform delta

3

3

High-throughput

0.650

High

1218008

SCNM1
Sodium channel modifier 1

3

0

High-throughput

0.646

High

1218026

AIRIM
AFG2-interacting ribosome maturation factor

3

0

High-throughput

0.646

High

1217976

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

3

0

High-throughput

0.638

High

650555

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

2

18

High-throughput

0.628

High

1217989

DYL2
Dynein light chain 2, cytoplasmic

3

7

High-throughput

0.624

High

279392

TULP3
Tubby-related protein 3

2

2

High-throughput

0.614

High

1118884

BYST
Bystin

2

0

High-throughput

0.612

High

248719

PEPL
Periplakin

2

18

High-throughput

0.611

High

445004

S10A9
Protein S100-A9

2

20

High-throughput

0.611

High

457872

INVO
Involucrin

2

7

High-throughput

0.611

High

568964

ANXA8
Annexin A8

2

5

High-throughput

0.611

High

577791

PLAK
Junction plakoglobin

2

14

High-throughput

0.611

High

692717

CALL3
Calmodulin-like protein 3

2

4

High-throughput

0.611

High

711709

RABP2
Cellular retinoic acid-binding protein 2

2

1

High-throughput

0.611

High

713394

SPB3
Serpin B3

2

5

High-throughput

0.611

High

724586

S10A7
Protein S100-A7

2

20

High-throughput

0.611

High

787660

SPB5
Serpin B5

2

5

High-throughput

0.611

High

868090

AL1A3
Retinaldehyde dehydrogenase 3

2

1

High-throughput

0.611

High

868711

LEG7
Galectin-7

2

10

High-throughput

0.611

High

874799

SPB4
Serpin B4

2

5

High-throughput

0.611

High

885810

KC1E
Casein kinase I isoform epsilon

2

5

High-throughput

0.611

High

945014

RAB25
Ras-related protein Rab-25

2

3

High-throughput

0.611

High

1210869

CE170
Centrosomal protein of 170 kDa

2

15

High-throughput

0.611

High

1218043

PKP3
Plakophilin-3

2

20

High-throughput

0.611

High

208849

ZBT24
Zinc finger and BTB domain-containing protein 24

2

1

High-throughput

0.606

High

478690

HXB5
Homeobox protein Hox-B5

2

1

High-throughput

0.606

High

725070

HXC8
Homeobox protein Hox-C8

2

1

High-throughput

0.606

High

1217962

ZN410
Zinc finger protein 410

2

3

High-throughput

0.606

High

1217998

ZN587
Zinc finger protein 587

2

2

High-throughput

0.606

High

1218005

ZKSC3
Zinc finger protein with KRAB and SCAN domains 3

2

4

High-throughput

0.606

High

1218032

ZBTB4
Zinc finger and BTB domain-containing protein 4

2

2

High-throughput

0.606

High

1218021

DISC1
Disrupted in schizophrenia 1 protein

2

7

High-throughput

0.596

High

791450

SYUA
Alpha-synuclein

2

5

High-throughput

0.595

High

1218001

CDC5L
Cell division cycle 5-like protein

2

5

High-throughput

0.590

High

1218038

TNIK
TRAF2 and NCK-interacting protein kinase

2

20

High-throughput

0.590

High

1217983

NDRG1
Protein NDRG1

2

0

High-throughput

0.585

High

1218000

NIBA2
Protein Niban 2

2

0

High-throughput

0.585

High

1156259

ZN124
Zinc finger protein 124

2

0

High-throughput

0.580

High

1217992

ZN414
Zinc finger protein 414

2

0

High-throughput

0.580

High

1218012

ZN696
Zinc finger protein 696

2

0

High-throughput

0.580

High

1218042

FA50B
Protein FAM50B

2

0

High-throughput

0.580

High

568816

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

2

10

Small-scale

0.576

High

69788

ZN785
Zinc finger protein 785

2

0

High-throughput

0.576

High

1217970

CA087
Uncharacterized protein C1orf87

2

1

High-throughput

0.574

High

965467

LMO4
LIM domain transcription factor LMO4

2

6

High-throughput

0.573

High

1161814

ZSC26
Zinc finger and SCAN domain-containing protein 26

1

3

High-throughput

0.573

High

1185251

F161A
Protein FAM161A

1

1

High-throughput

0.573

High

1205818

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

20

High-throughput

0.573

High

1217955

PPR18
Phostensin

1

7

High-throughput

0.573

High

1217956

KLC3
Kinesin light chain 3

1

4

High-throughput

0.573

High

1217979

AEN
Apoptosis-enhancing nuclease

1

2

High-throughput

0.573

High

1217988

HAUS1
HAUS augmin-like complex subunit 1

1

2

High-throughput

0.573

High

1218011

SH24A
SH2 domain-containing protein 4A

1

11

High-throughput

0.573

High

1218014

ZN408
Zinc finger protein 408

1

1

High-throughput

0.573

High

1164419

MIC60
MICOS complex subunit MIC60

2

1

High-throughput

0.566

High

1065948

VAC14
Protein VAC14 homolog

2

5

High-throughput

0.559

High

238669

AK1BA
Aldo-keto reductase family 1 member B10

2

1

High-throughput

0.558

High

369876

CO3
Complement C3

2

4

High-throughput

0.558

High

652330

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

1

High-throughput

0.558

High

888529

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

2

3

High-throughput

0.558

High

932825

HMCS2
Hydroxymethylglutaryl-CoA synthase, mitochondrial

2

1

High-throughput

0.558

High

1009662

NGAL
Neutrophil gelatinase-associated lipocalin

2

1

High-throughput

0.558

High

1156515

CCDC6
Coiled-coil domain-containing protein 6

2

18

High-throughput

0.558

High

1217954

P20D1
N-fatty-acyl-amino acid synthase/hydrolase PM20D1

2

1

High-throughput

0.558

High

1217985

EVPL
Envoplakin

2

19

High-throughput

0.558

High

1218037

CLC4K
C-type lectin domain family 4 member K

2

7

High-throughput

0.558

High

909964

MYOM1
Myomesin-1

2

14

High-throughput

0.553

High

1064382

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

1

Small-scale

0.552

High

1217965

DJC10
DnaJ homolog subfamily C member 10

2

4

High-throughput

0.549

High

72419

MI4GD
MIF4G domain-containing protein

1

0

High-throughput

0.549

High

1218023

SHFL
Shiftless antiviral inhibitor of ribosomal frameshifting protein

1

0

High-throughput

0.549

High

1218027

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.549

High

106095

APRIO
Alternative prion protein

2

6

Small-scale

0.543

High

1217973

CLIP4
CAP-Gly domain-containing linker protein 4

1

20

High-throughput

0.541

High

1218017

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

1

11

High-throughput

0.541

High

721016

CLIP1
CAP-Gly domain-containing linker protein 1

1

16

High-throughput

0.536

High

975082

ARF6
ADP-ribosylation factor 6

1

5

High-throughput

0.536

High

1217960

FBX50
F-box only protein 50

1

2

High-throughput

0.536

High

1218030

CALL5
Calmodulin-like protein 5

1

6

High-throughput

0.536

High

75680

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

2

4

High-throughput

0.533

High

1215280

UT14C
U3 small nucleolar RNA-associated protein 14 homolog C

2

2

High-throughput

0.526

High

1218004

ZFY21
Zinc finger FYVE domain-containing protein 21

1

10

High-throughput

0.523

High

1218025

FAME
Factor associated with metabolism and energy

1

1

High-throughput

0.523

High

539606

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.518

High

1217982

RSPH1
Radial spoke head 1 homolog

1

0

High-throughput

0.518

High

1218013

AKTIP
AKT-interacting protein

1

0

High-throughput

0.518

High

255815

USO1
General vesicular transport factor p115

1

19

Small-scale

0.515

High

447102

NPM
Nucleophosmin

1

5

High-throughput

0.515

High

1217986

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.515

High

1218044

TLN1
Talin-1

1

19

High-throughput

0.515

High

650220

FGFR3
Fibroblast growth factor receptor 3

1

7

High-throughput

0.515

High

1218010

Q9H6F0
cDNA: FLJ22332 fis, clone HRC05753

1

1

High-throughput

0.515

High

1145978

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.512

High

246663

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.508

High

375600

RASK
GTPase KRas

1

11

High-throughput

0.508

High

456109

FES
Tyrosine-protein kinase Fes/Fps

1

14

High-throughput

0.508

High

808089

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

High-throughput

0.508

High

908837

NEK2
Serine/threonine-protein kinase Nek2

1

20

High-throughput

0.508

High

1116421

FHL1
Four and a half LIM domains protein 1

1

8

High-throughput

0.508

High

1218007

TRAF4
TNF receptor-associated factor 4

1

20

Small-scale

0.508

High

249150

DSCAM
Cell adhesion molecule DSCAM

1

5

High-throughput

0.494

High

358051

ADH1B
All-trans-retinol dehydrogenase [NAD(+)] ADH1B

1

1

High-throughput

0.494

High

1125792

MYPC2
Myosin-binding protein C, fast-type

1

20

High-throughput

0.494

High

702455

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

261822

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.486

High

332158

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

1

0

High-throughput

0.486

High

405484

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

1160485

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

1218019

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.486

High

1218009

COMD4
COMM domain-containing protein 4

1

0

Small-scale

0.484

High

436897

K1C18
Keratin, type I cytoskeletal 18

1

16

High-throughput

0.481

High

451177

NFL
Neurofilament light polypeptide

1

18

High-throughput

0.481

High

538410

EGR2
E3 SUMO-protein ligase EGR2

1

2

High-throughput

0.481

High

1217723

GFI1B
Zinc finger protein Gfi-1b

1

2

High-throughput

0.481

High

1217957

ANR11
Ankyrin repeat domain-containing protein 11

1

12

High-throughput

0.481

High

1217972

PIAS4
E3 SUMO-protein ligase PIAS4

1

4

High-throughput

0.481

High

1217975

ZBT38
Zinc finger and BTB domain-containing protein 38

1

3

High-throughput

0.481

High

1218022

KLC4
Kinesin light chain 4

1

6

High-throughput

0.481

High

1218029

ITSN2
Intersectin-2

1

6

High-throughput

0.481

High

1218033

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.481

High

404819

PRIO
Major prion protein

1

0

Small-scale

0.480

High

159691

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

8

High-throughput

0.479

High

241952

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

251221

RNBP6
Ran-binding protein 6

1

2

High-throughput

0.479

High

440593

FYN
Tyrosine-protein kinase Fyn

1

12

Small-scale

0.479

High

603292

KPCA
Protein kinase C alpha type

1

13

High-throughput

0.479

High

623384

RO52
E3 ubiquitin-protein ligase TRIM21

1

11

High-throughput

0.479

High

830898

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

960451

PSME3
Proteasome activator complex subunit 3

1

3

Small-scale

0.479

High

1094910

TRAF3
TNF receptor-associated factor 3

1

20

Small-scale

0.479

High

1113350

CUL3
Cullin-3

1

15

High-throughput

0.479

High

1117948

PKP1
Plakophilin-1

1

20

High-throughput

0.479

High

1140402

KIF14
Kinesin-like protein KIF14

1

17

High-throughput

0.479

High

1217958

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1217990

S10AG
Protein S100-A16

1

20

High-throughput

0.479

High

1217999

OSBL9
Oxysterol-binding protein-related protein 9

1

1

Small-scale

0.479

High

1218002

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1218006

NAA11
N-alpha-acetyltransferase 11

1

1

High-throughput

0.479

High

1218015

CLXN
Calaxin

1

4

High-throughput

0.479

High

1218020

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

4

High-throughput

0.479

High

1218034

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1218035

SWP70
Switch-associated protein 70

1

20

High-throughput

0.479

High

1218040

SNX6
Sorting nexin-6

1

1

High-throughput

0.479

High

207825

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

8

High-throughput

0.470

High

97286

E9PSE9
Coiled-coil domain containing 198

1

1

High-throughput

0.470

High

1066091

Q08E77
UTP14, U3 small nucleolar ribonucleoprotein, homolog C

1

2

High-throughput

0.470

High

1068821

GOG8D
Putative golgin subfamily A member 8D

1

11

High-throughput

0.470

High

1217984

HMHA1
Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1

1

7

High-throughput

0.470

High

1217993

Z512B
Zinc finger protein 512B

1

12

High-throughput

0.464

High

1133320

MYPC3
Myosin-binding protein C, cardiac-type

1

20

Small-scale

0.462

High

1150199

TEAD4
Transcriptional enhancer factor TEF-3

1

0

High-throughput

0.460

High

904431

CP2J2
Cytochrome P450 2J2

1

0

High-throughput

0.458

High

1218018

S40A1
Ferroportin

1

0

High-throughput

0.458

High

3245

A0A0S2Z3U4
E3 SUMO-protein ligase EGR2

1

4

High-throughput

0.457

High

249619

SNX3
Sorting nexin-3

1

1

Small-scale

0.457

High

445915

ENOA
Alpha-enolase

1

8

Small-scale

0.457

High

531085

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

14

Small-scale

0.457

High

1146277

ANKR1
Ankyrin repeat domain-containing protein 1

1

14

Small-scale

0.457

High

1217978

ZN417
Zinc finger protein 417

1

2

High-throughput

0.457

High

1218047

X5DP31
Aryl hydrocarbon receptor nuclear translocator 2

1

11

High-throughput

0.457

High

543517

VDR
Vitamin D3 receptor

1

13

High-throughput

0.445

High

934731

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.445

High

942678

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

20

High-throughput

0.445

High

1119166

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

15

High-throughput

0.445

High

1154376

STK11
Serine/threonine-protein kinase STK11

1

4

High-throughput

0.445

High

1217963

CEP57
Centrosomal protein of 57 kDa

1

2

High-throughput

0.445

High

1217974

RYBP
RING1 and YY1-binding protein

1

3

High-throughput

0.445

High

1217977

CTCFL
Transcriptional repressor CTCFL

1

3

High-throughput

0.445

High

1217996

CEP63
Centrosomal protein of 63 kDa

1

19

High-throughput

0.445

High

319220

FCSD2
F-BAR and double SH3 domains protein 2

1

6

High-throughput

0.439

High

1217971

UB2J2
Ubiquitin-conjugating enzyme E2 J2

1

0

High-throughput

0.438

High

914273

EFNA4
Ephrin-A4

1

7

High-throughput

0.437

High

945531

SNX16
Sorting nexin-16

1

1

High-throughput

0.437

High

1063786

LG3BP
Galectin-3-binding protein

1

13

Small-scale

0.437

High

1143153

PLEC
Plectin

1

20

Small-scale

0.437

High

1147531

UBE3C
Ubiquitin-protein ligase E3C

1

9

High-throughput

0.437

High

1217968

FAM9C
Protein FAM9C

1

2

High-throughput

0.437

High

1218039

AT7L1
Ataxin-7-like protein 1

1

8

High-throughput

0.437

High

1218045

O10H1
Olfactory receptor 10H1

1

1

High-throughput

0.437

High

335469

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.426

High

1218016

ROP1A
Ropporin-1A

1

0

High-throughput

0.426

High

569018

ENOB
Beta-enolase

1

8

Small-scale

0.417

High

622503

TNNI3
Troponin I, cardiac muscle

1

1

Small-scale

0.417

High

634117

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

1

Small-scale

0.417

High

1218046

X5D778
Ankyrin repeat domain 11 isoform A

1

13

High-throughput

0.417

High

69502

A2ML1
Alpha-2-macroglobulin-like protein 1

1

4

High-throughput

0.407

High

255066

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.407

High

379103

IGKC
Immunoglobulin kappa constant

1

2

High-throughput

0.407

High

379257

IGHG1
Immunoglobulin heavy constant gamma 1

1

7

High-throughput

0.407

High

379360

IGHG2
Immunoglobulin heavy constant gamma 2

1

6

High-throughput

0.407

High

1178998

S35G1
Solute carrier family 35 member G1

1

2

High-throughput

0.407

High

1217966

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

3

High-throughput

0.407

High

1217969

SYCE1
Synaptonemal complex central element protein 1

1

2

High-throughput

0.407

High

1217994

C170L
Cep170-like protein

1

7

High-throughput

0.407

High

1217995

RN145
RING finger protein 145

1

7

High-throughput

0.407

High

609312

SAP3
Ganglioside GM2 activator

2

0

High-throughput

0.318

High

627131

TYPH
Thymidine phosphorylase

2

0

High-throughput

0.318

High

895324

GATM
Glycine amidinotransferase, mitochondrial

2

0

High-throughput

0.318

High

1217961

GDPD3
Lysophospholipase D GDPD3

2

0

High-throughput

0.318

High

1217980

POF1B
Protein POF1B

2

0

High-throughput

0.318

High

1180443

C19L2
CWF19-like protein 2

2

0

High-throughput

0.316

High

1217991

LIN37
Protein lin-37 homolog

2

0

High-throughput

0.316

High

1135974

RTP5
Receptor-transporting protein 5

1

0

High-throughput

0.299

High

1217987

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.299

High

1154314

CYTM
Cystatin-M

1

0

High-throughput

0.279

Low

1218036

LTOR3
Ragulator complex protein LAMTOR3

1

0

High-throughput

0.265

Low

1142793

PEA15
Astrocytic phosphoprotein PEA-15

1

0

Small-scale

0.251

Low

892973

ENTP1
Ectonucleoside triphosphate diphosphohydrolase 1

1

0

High-throughput

0.249

Low

1218028

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

947010

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

260720

RAMP1
Receptor activity-modifying protein 1

1

0

High-throughput

0.232

Low

947895

T2R31
Taste receptor type 2 member 31

1

0

High-throughput

0.232

Low

1059117

PIGF
GPI ethanolamine phosphate transferase, stabilizing subunit

1

0

High-throughput

0.232

Low

1217959

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.232

Low

1217964

CCD71
Coiled-coil domain-containing protein 71

1

0

High-throughput

0.232

Low

1218024

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025