HitPredict

Interactor 1: SMAD1 (Q15797)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
Gene: SMAD1

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12650946
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 1356
+	Hs
		1014558 SMAD3_HUMAN (3-465): 0: 556: 59.66		PARD3_HUMAN (1-1356): 0: 706: 100.00
+	Hs
		1153844 SMAD2_HUMAN (3-465): 0: 541: 55.14		PARD3_HUMAN (1-1356): 0: 706: 100.00
+	Hs
		1106627 SMAD4_HUMAN (13-454): 1.61e-150: 441: 34.28		PARD3_HUMAN (1-1356): 0: 706: 100.00
+	Hs
		177697 SMAD7_HUMAN (30-131): 2.9e-25: 109: 32.46		PARD3_HUMAN (1-1356): 0: 706: 100.00
+	Dm
		837143 MAD_DROME (2-465): 0: 594: 72.85		SCRIB_DROME (554-719): 3.84e-13: 76.7: 22.49
+	Hs
		1014673 SMAD3_HUMAN (3-465): 0: 556: 59.66		GRIP1_HUMAN (239-1319): 4.93e-24: 112: 10.37
+	Mm
		1297412 SMAD3_MOUSE (3-465): 0: 556: 59.66		MAGI2_MOUSE (130-412): 8.07e-16: 85.4: 11.81