HitPredict

Interactor 1: EREP1 (Q15884)
Endosomal transmembrane epsin interactor 1 (Endosomal transmembrane binding with epsin)
Gene: ENTREP1

Interactor 2: WWC2 (Q6AWC2)
Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2)
Gene: WWC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	34927784
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 1192
+	Hs
		1155186 EREP1_HUMAN (1-450): 0: 619: 100.00		WWP1_HUMAN (6-143): 3.65e-36: 150: 22.67
+	Hs
		1155197 EREP1_HUMAN (1-450): 0: 619: 100.00		WWOX_HUMAN (5-193): 8.82e-38: 149: 20.71
+	Hs
		1155174 EREP1_HUMAN (1-450): 0: 619: 100.00		ITCH_HUMAN (10-143): 1.83e-32: 138: 24.83
+	Hs
		132069 EREP1_HUMAN (1-450): 0: 619: 100.00		WWP2_HUMAN (3-143): 7.2e-31: 133: 23.84
+	Hs
		861620 EREP1_HUMAN (1-450): 0: 619: 100.00		NEDD4_HUMAN (4-295): 3.75e-18: 92.7: 14.93
+	Hs
		1155176 EREP1_HUMAN (1-450): 0: 619: 100.00		NED4L_HUMAN (7-163): 9.72e-18: 91.2: 14.65
+	Hs
		1010530 EREP3_HUMAN (3-317): 4.93e-89: 286: 26.38		WWP1_HUMAN (6-143): 3.65e-36: 150: 22.67
+	Hs
		1010540 EREP3_HUMAN (3-317): 4.93e-89: 286: 26.38		WWOX_HUMAN (5-193): 8.82e-38: 149: 20.71
+	Hs
		1010516 EREP3_HUMAN (3-317): 4.93e-89: 286: 26.38		ITCH_HUMAN (10-143): 1.83e-32: 138: 24.83
+	Hs
		131944 EREP3_HUMAN (3-317): 4.93e-89: 286: 26.38		WWP2_HUMAN (3-143): 7.2e-31: 133: 23.84
+	Hs
		861564 EREP3_HUMAN (3-317): 4.93e-89: 286: 26.38		NEDD4_HUMAN (4-295): 3.75e-18: 92.7: 14.93
+	Hs
		1010517 EREP3_HUMAN (3-317): 4.93e-89: 286: 26.38		NED4L_HUMAN (7-163): 9.72e-18: 91.2: 14.65
+	Hs
		1356219 Q8WU02_HUMAN (162-318): 1.1e-65: 210: 81.53		WWP1_HUMAN (6-143): 3.65e-36: 150: 22.67
+	Hs
		132181 Q8WU02_HUMAN (162-318): 1.1e-65: 210: 81.53		WWP2_HUMAN (3-143): 7.2e-31: 133: 23.84